{"id":"W1493565145","doi":"10.1186/s12896-015-0152-x","title":"Critical assessment of influenza VLP production in Sf9 and HEK293 expression systems","year":2015,"lang":"en","type":"article","venue":"BMC Biotechnology","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Waterloo; Polytechnique Montréal; National Research Council Canada","funders":"Natural Sciences and Engineering Research Council of Canada; University of Waterloo","keywords":"Sf9; Virology; HEK 293 cells; Biology; Virus; Virus-like particle; Viral matrix protein; Hemagglutinin (influenza); Influenza vaccine; Cell culture; Genetics; Gene; Recombinant DNA; Spodoptera","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002006652,0.0001134307,0.0001704793,0.0001150747,0.00003233701,0.00001182218,0.0001014712,0.0003977399,0.000002678641],"category_scores_gemma":[0.0004949722,0.0001009149,0.0000301519,0.0001141354,0.0001965784,0.000007186563,0.0001781981,0.0001202161,0.000001453094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001946246,"about_ca_system_score_gemma":0.00009467743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004981194,"about_ca_topic_score_gemma":0.00002403967,"domain_scores_codex":[0.9990402,0.00009101364,0.0002494102,0.0003429471,0.0001019912,0.0001743759],"domain_scores_gemma":[0.9994189,0.00001159792,0.00007554897,0.0003304779,0.00009165347,0.00007182699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008324751,0.0001581689,0.06180345,0.0001110364,0.000007771268,0.000002117245,0.00001779383,0.000455167,0.9338273,0.001381802,0.001737127,0.0004149743],"study_design_scores_gemma":[0.001130882,0.001067183,0.0145618,0.0001514889,0.00001578487,0.00007220039,0.0005365339,0.000604051,0.9707819,0.0009534055,0.00983228,0.0002925536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930872,0.002565476,0.003190123,0.0001744565,0.0004777946,0.00021293,0.00000774564,0.00003119306,0.0002530454],"genre_scores_gemma":[0.9972443,0.0001113268,0.002391322,0.0000454802,0.00009717853,0.00005114864,0.000009354588,0.00001154122,0.00003837422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04724165,"threshold_uncertainty_score":0.4115188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02945411602883017,"score_gpt":0.3371386211742962,"score_spread":0.307684505145466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}