{"id":"W1494263088","doi":"10.1111/j.1755-5949.2012.00316.x","title":"Dietary Vitamin D<sub>3</sub> Supplementation at 10× the Adequate Intake Improves Functional Capacity in the G93A Transgenic Mouse Model of ALS, a Pilot Study","year":2012,"lang":"en","type":"article","venue":"CNS Neuroscience & Therapeutics","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; York University","funders":"Natural Sciences and Engineering Research Council of Canada; York University","keywords":"Medicine; Genetically modified mouse; Vitamin; Transgene; Vitamin D and neurology; Rodent model; Food intake; Physiology; Gerontology; Biology; Endocrinology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003895006,0.000936816,0.001120949,0.0008185055,0.0003123724,0.0005426968,0.0004884914,0.000800497,0.001910718],"category_scores_gemma":[0.0001491279,0.0002911926,0.0008142561,0.0003870623,0.0006605425,0.0004216762,0.0003614782,0.001877488,0.0004533214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005223816,"about_ca_system_score_gemma":0.000497905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001454161,"about_ca_topic_score_gemma":0.004083374,"domain_scores_codex":[0.9997196,0.00003056891,0.00004498634,0.00007027856,0.00006874817,0.0000659339],"domain_scores_gemma":[0.9995634,0.00002571241,0.000173051,0.00004611848,0.00004767983,0.0001440933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007762709,0.001972989,0.0008284471,0.000211769,0.00007892901,0.00008186229,0.00004385773,0.0001108682,0.9838899,0.00003728666,0.0002137114,0.004767643],"study_design_scores_gemma":[0.001837738,0.05816928,0.02761118,0.0001181268,0.0005507091,0.0006240875,0.0002579823,0.0007761179,0.9040774,0.0001893908,0.005735025,0.00005304349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951767,0.001872513,0.0008910752,0.0001811794,0.00005850508,0.0001033707,0.001020803,0.0001419687,0.000553855],"genre_scores_gemma":[0.9838462,0.00254463,0.004817876,0.0003523903,0.00004272016,0.0004365284,0.002534111,0.00008587135,0.005339675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001910718,"threshold_uncertainty_score":0.006392002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2660121906436746,"score_gpt":0.3314144374377154,"score_spread":0.06540224679404077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}