{"id":"W1494843398","doi":"10.4049/jimmunol.175.9.6197","title":"CD80/CD86 Costimulation Regulates Acute Vascular Rejection","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Robarts Clinical Trials; London Health Sciences Centre; Hospital for Sick Children; University of Toronto; Toronto General Hospital; University Health Network; Western University","funders":"Canadian Institutes of Health Research; Genome Canada","keywords":"Xenotransplantation; CD86; CD80; Medicine; Immunology; Transplantation; Biology; Immune system; Internal medicine; T cell; In vitro; Cytotoxic T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009704292,0.0002671826,0.0001284426,0.0001408549,0.0001347259,0.0003215429,0.0001182298,0.0001931005,0.0009458894],"category_scores_gemma":[0.00007552152,0.00007552735,0.0001021596,0.00006230047,0.0001722148,0.0001703338,0.0001611549,0.0005363554,0.0002546702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001748447,"about_ca_system_score_gemma":0.0001328776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001105736,"about_ca_topic_score_gemma":0.0002232875,"domain_scores_codex":[0.9998791,0.00002136957,0.000009686422,0.00001882929,0.00002182596,0.00004922794],"domain_scores_gemma":[0.9999099,0.000006603055,0.00003395014,0.000004586399,0.00000776215,0.00003726454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001347436,0.00005366834,0.0009647564,0.00002275538,0.000002427821,0.00004961176,0.00001464049,0.00005041125,0.9966525,0.0001322963,0.00003110673,0.001891133],"study_design_scores_gemma":[0.0001116675,0.001498674,0.07153387,0.00003615114,0.00007789896,0.0009450591,0.0001732892,0.004021145,0.9160605,0.0003754996,0.005156143,0.00001007562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974801,0.001062341,0.000543742,0.00004864251,0.000009033891,0.000006786097,0.00002819231,0.00001523904,0.0008059617],"genre_scores_gemma":[0.9980616,0.0006647556,0.0002836726,0.00003091302,0.00001378805,0.00000936503,0.00004578732,0.000003841664,0.0008862726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009458894,"threshold_uncertainty_score":0.003164351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019171530839158,"score_gpt":0.2717586042961579,"score_spread":0.2615668889877663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}