{"id":"W1495281777","doi":"10.1038/nrc1042","title":"Challenges to cancer control by screening","year":2003,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"McGill University","keywords":"Cancer screening; Cancer; Medicine; Risk analysis (engineering); Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005935044,0.0008851843,0.002244041,0.0001272634,0.0001129994,0.00004568713,0.0007567692,0.001704627,0.0002920642],"category_scores_gemma":[0.000211896,0.0007181625,0.0008437882,0.0004420166,0.00006093471,0.00000582235,0.0001192558,0.001107991,0.00007398493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004281474,"about_ca_system_score_gemma":0.0008851818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000213138,"about_ca_topic_score_gemma":0.0002320626,"domain_scores_codex":[0.9963387,0.0004609291,0.000848332,0.001398163,0.0003328905,0.0006209552],"domain_scores_gemma":[0.9977671,0.00004431279,0.0005994114,0.001111282,0.0002209272,0.000256976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005409896,0.00001386604,0.000001339233,0.004872108,0.0003256964,0.000001045119,0.000009014838,0.000006062914,0.0000313023,0.00001436357,0.2349754,0.7597444],"study_design_scores_gemma":[0.0002778937,0.00005009674,7.738921e-7,0.01036962,0.0009381499,0.00001623334,0.000004134253,3.366276e-7,0.00005121733,0.000002579344,0.9874867,0.0008022744],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[2.569185e-7,0.9924729,0.0004609019,0.0005507798,0.001581135,0.002472331,0.0008912973,0.00002296027,0.00154742],"genre_scores_gemma":[0.000002980948,0.9848645,0.0007308616,0.003717174,0.001759891,0.005714293,0.0002971613,0.0001950187,0.002718171],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7589421,"threshold_uncertainty_score":0.9995914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05158613766140375,"score_gpt":0.4042264709038611,"score_spread":0.3526403332424574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}