{"id":"W1496090907","doi":"10.1096/fasebj.29.1_supplement.715.32","title":"Exogenous Arachidonic Acid Mediates Permeability of Human Brain Microvessel Endothelial Cells through Prostaglandin E <sub>2</sub> Activation of EP <sub>3</sub> and EP <sub>4</sub> Receptors","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Arachidonic acid; Microvessel; Chemistry; Receptor; Blood–brain barrier; Prostaglandin; Vascular permeability; Permeability (electromagnetism); Cyclooxygenase; Endothelial stem cell; Parenchyma; Biochemistry; Prostaglandin D2; Cell biology; Endocrinology; Biology; Angiogenesis; In vitro; Membrane; Cancer research; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000183244,0.000290191,0.0002855144,0.0001507197,0.0001924452,0.0003677902,0.0001782004,0.000295219,0.001838418],"category_scores_gemma":[0.0002270799,0.0001671517,0.0003423543,0.0001364471,0.0001466874,0.0003725224,0.0002181865,0.0005905714,0.0005465082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002411017,"about_ca_system_score_gemma":0.0001940825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001631286,"about_ca_topic_score_gemma":0.001532616,"domain_scores_codex":[0.9997907,0.00006167501,0.0000160248,0.0000258749,0.00004129347,0.00006452407],"domain_scores_gemma":[0.9999321,0.00002026811,0.00001518226,0.000009371957,0.00001317118,0.00001007242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000263655,0.00004249734,0.0001999016,0.00007608407,0.00001062787,0.0001386265,0.00005001997,0.0000327627,0.9970781,0.000140445,0.0001132173,0.0018542],"study_design_scores_gemma":[0.00003242942,0.0005297974,0.01065615,0.00001837724,0.00004496145,0.0004486403,0.0001076833,0.001089475,0.9832866,0.0001540243,0.003621054,0.0000107541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843317,0.007095099,0.004684349,0.000268989,0.00007958697,0.00004439625,0.0004286565,0.0000952109,0.002971965],"genre_scores_gemma":[0.9887112,0.004120808,0.002994214,0.0001540659,0.00003061161,0.0000643212,0.0005571198,0.00001431878,0.0033532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001838418,"threshold_uncertainty_score":0.006150126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01865076926754443,"score_gpt":0.2524159687152614,"score_spread":0.233765199447717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}