{"id":"W1496127239","doi":"10.1034/j.1399-0004.2001.590210.x","title":"The ‘flap’ endonuclease gene FEN1 is excluded as a candidate gene implicated in the CAG repeat expansion underlying Huntington disease","year":2001,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Huntington Society of Canada","keywords":"Trinucleotide repeat expansion; Biology; Genetics; Gene; DNA repair; Allele","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001889945,0.0003141246,0.0002725698,0.0005096353,0.0003546799,0.0001577393,0.0003080152,0.0003254359,0.002254176],"category_scores_gemma":[0.0006547777,0.000129324,0.0001437107,0.0002017472,0.00033288,0.0001344668,0.0002128941,0.0001876165,0.0001994844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000173384,"about_ca_system_score_gemma":0.0001315377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001054264,"about_ca_topic_score_gemma":0.001748805,"domain_scores_codex":[0.9998713,0.00002308306,0.00001127935,0.00004129096,0.00003078206,0.00002231184],"domain_scores_gemma":[0.9997817,0.00007381199,0.00007335318,0.00001305894,0.00002024994,0.00003792384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001882836,0.0001631115,0.4078442,0.0002035296,0.0001710214,0.03727525,0.001035866,0.0004383826,0.5118572,0.0008011612,0.0004472891,0.03788009],"study_design_scores_gemma":[0.00005609815,0.0005698084,0.8468882,0.00006941216,0.0001952601,0.07746778,0.0004818775,0.001055048,0.06731085,0.0005335345,0.005351744,0.00002043049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991359,0.0002538088,0.0002017846,0.00002908164,0.000001909624,0.000001995064,0.00005919898,0.000003815056,0.0003125241],"genre_scores_gemma":[0.9988213,0.0001679448,0.0004664001,0.00002402056,0.00000366064,0.000002465389,0.0001528784,0.000003535513,0.0003576462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002254176,"threshold_uncertainty_score":0.007541001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1319908657585995,"score_gpt":0.3929759466277183,"score_spread":0.2609850808691188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}