{"id":"W1496225458","doi":"10.1002/chin.200006132","title":"ChemInform Abstract: Synthesis, Calcium Channel Antagonist Activity, and Anticonvulsant Activity of 3‐Ethyl 5‐Methyl 1,4‐Dihydro‐2‐ [(2‐hydroxyethoxy)methyl] ‐6‐methyl‐4‐(2,3‐dichlorophenyl)‐3,5‐pyridinecarboxylate Coupled to a 1‐Methyl‐1,4‐dihydropyridyl‐3‐carbonyl Chemical Delivery System.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and Reactivity of Heterocycles","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Antagonist; Stereochemistry; Combinatorial chemistry; Anticonvulsant; Biochemistry; Neuroscience; Psychology; Epilepsy; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001627232,0.002125719,0.003434852,0.000582533,0.0006204857,0.0003763268,0.001688334,0.001717677,0.002047296],"category_scores_gemma":[0.0007956599,0.002051729,0.001132713,0.000826575,0.001118849,0.001336383,0.0008517038,0.001789712,0.0001589507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009112058,"about_ca_system_score_gemma":0.0003951401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002750646,"about_ca_topic_score_gemma":0.00003781834,"domain_scores_codex":[0.9913264,0.000008832593,0.002102044,0.002145334,0.00197069,0.002446695],"domain_scores_gemma":[0.992203,0.002136829,0.001374114,0.002387319,0.000349436,0.001549292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001292307,0.0005981958,0.00003484996,0.002282053,0.0005479006,0.00007965467,0.0007714317,0.00001014234,0.7423522,0.00001412807,0.0002704672,0.2517467],"study_design_scores_gemma":[0.00188352,0.0001277648,0.0007140358,0.001389386,0.0005884911,0.0002664679,0.0006732398,0.00321887,0.9859532,0.00004845875,0.002857614,0.002278983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8718753,0.0007697305,0.000003895973,0.0004581582,0.0003027301,0.0008107772,0.0003705074,0.0005682308,0.1248407],"genre_scores_gemma":[0.9950065,0.0009191468,0.0002021656,0.0001230401,0.0007254732,0.0003603472,0.00007052672,0.000319624,0.002273151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2494677,"threshold_uncertainty_score":0.9995783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01592979675977067,"score_gpt":0.2427758074914985,"score_spread":0.2268460107317278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}