{"id":"W1496225458","doi":"10.1002/chin.200006132","title":"ChemInform Abstract: Synthesis, Calcium Channel Antagonist Activity, and Anticonvulsant Activity of 3‐Ethyl 5‐Methyl 1,4‐Dihydro‐2‐ [(2‐hydroxyethoxy)methyl] ‐6‐methyl‐4‐(2,3‐dichlorophenyl)‐3,5‐pyridinecarboxylate Coupled to a 1‐Methyl‐1,4‐dihydropyridyl‐3‐carbonyl Chemical Delivery System.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and Reactivity of Heterocycles","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Antagonist; Stereochemistry; Combinatorial chemistry; Anticonvulsant; Biochemistry; Neuroscience; Psychology; Epilepsy; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001285685,0.0006603751,0.0003294984,0.0003188256,0.000224515,0.0002401711,0.000381075,0.0003271402,0.006753531],"category_scores_gemma":[0.0001051987,0.0002303018,0.0002234259,0.0002573137,0.0001695315,0.0002889181,0.000132841,0.0004397643,0.002334352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005078602,"about_ca_system_score_gemma":0.0007314786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009227594,"about_ca_topic_score_gemma":0.001528828,"domain_scores_codex":[0.9999324,0.000009452935,0.000005267511,0.00001582094,0.00001978327,0.00001733788],"domain_scores_gemma":[0.9999503,0.000006549604,0.00001394609,0.000004543407,0.000006361664,0.00001839152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000651229,0.0001401903,0.00006642772,0.000298503,0.00002408346,0.0001979906,0.00002484814,0.0004444349,0.9729787,0.0008547807,0.002233674,0.02208496],"study_design_scores_gemma":[0.0002164139,0.00162501,0.001149645,0.0000179801,0.00004003266,0.0004403207,0.000008223915,0.0005318491,0.9824964,0.0001145853,0.01334152,0.00001790863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8611742,0.02650969,0.01554358,0.0009308453,0.0005354359,0.0004966928,0.0050907,0.001065745,0.088653],"genre_scores_gemma":[0.9288477,0.01348188,0.007709976,0.0003849077,0.0001803582,0.0001889169,0.003838143,0.0001433388,0.04522494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006753531,"threshold_uncertainty_score":0.02259284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01592979675977067,"score_gpt":0.2427758074914985,"score_spread":0.2268460107317278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}