{"id":"W1496822412","doi":"10.1111/j.1471-4159.2005.03102.x","title":"Beta‐amyloid peptides stimulate endozepine biosynthesis in cultured rat astrocytes","year":2005,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Institut National de la Santé et de la Recherche Médicale","keywords":"Cycloheximide; Astrocyte; Gene expression; Biosynthesis; Biology; Peptide; Amyloid precursor protein; Alzheimer's disease; Protein biosynthesis; Molecular biology; Cell biology; Chemistry; Biochemistry; Endocrinology; Internal medicine; Gene; Central nervous system; Disease; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014161,0.0004497997,0.0003718189,0.0002102745,0.0001312687,0.0002378629,0.0001134059,0.0001448585,0.0007271002],"category_scores_gemma":[0.00009592433,0.0001365845,0.0003528962,0.000171402,0.0001340496,0.0001529813,0.0001964835,0.0003431436,0.0005251064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001803675,"about_ca_system_score_gemma":0.0001763864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00106285,"about_ca_topic_score_gemma":0.001889487,"domain_scores_codex":[0.999876,0.00001827865,0.0000129709,0.0000187872,0.00004148231,0.00003242366],"domain_scores_gemma":[0.9998891,0.00002427808,0.00001820468,0.00001779514,0.0000201194,0.00003039832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001591609,0.00003591773,0.0001711093,0.0000412029,0.00000552368,0.0001137785,0.00002439368,0.00003268407,0.9982431,0.00003787977,0.00002324071,0.00111221],"study_design_scores_gemma":[0.00002411108,0.0004656076,0.004909737,0.000006608521,0.00001863453,0.0002188327,0.00004019297,0.0003626777,0.9923118,0.00005662752,0.001581307,0.000003806158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901427,0.003245245,0.002113129,0.00006262086,0.00005745444,0.00004403194,0.0004859839,0.00009074376,0.003758091],"genre_scores_gemma":[0.9875019,0.003129733,0.004508106,0.00006943431,0.00003240251,0.00005406317,0.0006080095,0.00002856843,0.004067955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00106285,"threshold_uncertainty_score":0.002432346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02108558197822504,"score_gpt":0.300372331897991,"score_spread":0.279286749919766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}