{"id":"W1497269238","doi":"10.1111/j.1742-4658.2006.05121.x","title":"Activation of the<i>Torpedo</i>nicotinic acetylcholine receptor","year":2006,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Torpedo; Acetylcholine receptor; Nicotinic acetylcholine receptor; Receptor; Alpha-4 beta-2 nicotinic receptor; Nicotinic agonist; Chemistry; Cys-loop receptors; Acetylcholine; Ganglion type nicotinic receptor; Biophysics; Binding site; Stereochemistry; Biochemistry; Biology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009048664,0.0003694248,0.0002845027,0.00006054767,0.0001500733,0.0003450349,0.0003084998,0.0002096899,0.001432876],"category_scores_gemma":[0.0001503003,0.00008975455,0.0002208604,0.00006670813,0.0003101835,0.0001581802,0.0002843086,0.0004546001,0.0002836853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003678042,"about_ca_system_score_gemma":0.0001288833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009898108,"about_ca_topic_score_gemma":0.00105576,"domain_scores_codex":[0.999867,0.00001956406,0.00001042153,0.00003453648,0.00003815276,0.00003037347],"domain_scores_gemma":[0.9999516,0.000007745488,0.00001868782,0.000004944803,0.00000579302,0.00001112583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001434148,0.000008606918,0.0001254318,0.00005242014,0.000007592724,0.00009670491,0.000009504792,0.00007371037,0.9981293,0.0001654768,0.00004948218,0.001138346],"study_design_scores_gemma":[0.0000329759,0.0003195388,0.005047047,0.0000139582,0.00003951847,0.0009496768,0.00005606666,0.001555517,0.9880782,0.0001006411,0.003792873,0.00001393268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928578,0.001345298,0.001693642,0.0001072254,0.00004535933,0.00002333959,0.0001724766,0.00005425168,0.003700532],"genre_scores_gemma":[0.996893,0.0007614697,0.0009406447,0.0000747479,0.000005797213,0.000009643404,0.0001361953,0.000008270425,0.001170196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001432876,"threshold_uncertainty_score":0.004793406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006437831612766289,"score_gpt":0.2361112140280048,"score_spread":0.2296733824152385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}