{"id":"W1497897430","doi":"10.1186/ar1402","title":"15-Deoxy-Δ(12,14)-prostaglandin J(2 )inhibits IL-1β-induced cyclooxygenase-2 expression in human synovial fibroblasts through a histone deacetylase-independent mechanism","year":2004,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Hôpital Notre-Dame","funders":"Canadian Arthritis Network; School of Medicine, University of California, San Diego; Menzies Institute for Medical Research; National Cancer Institute; Arthritis Society; University of North Carolina at Chapel Hill; Genentech; National Institutes of Health; Biogen; Lupus Research Institute; Pfizer; Natural Sciences and Engineering Research Council of Canada; Dutch Arthritis Association; Oesterreichische Nationalbank; Deutsche Forschungsgemeinschaft; Nuffield Foundation; Physiotherapy Foundation of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lupus Research Alliance; Wellcome Trust; Newcastle University; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Austrian Science Fund; Arthritis Foundation","keywords":"Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002162128,0.0004841135,0.0008159602,0.0007275482,0.0006441728,0.000101292,0.0003388897,0.0005657418,0.0004972444],"category_scores_gemma":[0.0006048074,0.0004615157,0.0002170428,0.0006720455,0.0002445401,0.0004249722,0.000372661,0.001851395,0.0006588722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001006956,"about_ca_system_score_gemma":0.0006524703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001179672,"about_ca_topic_score_gemma":0.003141718,"domain_scores_codex":[0.9934162,0.0005568886,0.0008408528,0.00110469,0.002360216,0.0017211],"domain_scores_gemma":[0.9977736,0.0002147384,0.0001349223,0.0008971558,0.000327503,0.0006520697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000679161,0.0006841942,0.000480521,0.0002491424,0.0000282317,0.003165266,0.002414654,0.0000162871,0.9861963,0.002370513,0.001239944,0.002475834],"study_design_scores_gemma":[0.015252,0.002525032,0.002982617,0.002936105,0.0000111862,0.0002530671,0.0004113715,0.00002964774,0.969261,0.004801697,0.001033793,0.0005024832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932464,0.0007536833,0.0001342107,0.0006033218,0.0004452598,0.002296625,0.00003627386,0.0001764648,0.002307746],"genre_scores_gemma":[0.9967005,0.0005370691,0.0005607376,0.0001558109,0.0007236534,0.0004080447,0.0000981746,0.0001303387,0.0006856712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01693525,"threshold_uncertainty_score":0.9997836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0424883785013284,"score_gpt":0.3546818630037827,"score_spread":0.3121934845024543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}