{"id":"W1498149942","doi":"10.1186/s12885-015-1529-x","title":"TOPGEAR: a randomised phase III trial of perioperative ECF chemotherapy versus preoperative chemoradiation plus perioperative ECF chemotherapy for resectable gastric cancer (an international, intergroup trial of the AGITG/TROG/EORTC/NCIC CTG)","year":2015,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Gastric Cancer Management and Outcomes","field":"Medicine","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Toronto General Hospital; Mount Sinai Hospital","funders":"National Health and Medical Research Council; Medical Research Council","keywords":"Medicine; Perioperative; Epirubicin; Chemoradiotherapy; Chemotherapy; Surgery; Cancer; Randomized controlled trial; Surgical oncology; Clinical endpoint; Chemotherapy regimen; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007188062,0.000445402,0.001174972,0.0002366556,0.0001400954,0.00008902093,0.000466854,0.0001550121,0.0008378375],"category_scores_gemma":[0.0004437872,0.0003203705,0.0004940451,0.0005832864,0.0002482805,0.0004825574,0.00007733528,0.0002543518,0.000001590805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001404132,"about_ca_system_score_gemma":0.002163542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001564436,"about_ca_topic_score_gemma":0.001573764,"domain_scores_codex":[0.9969786,0.0001940571,0.0009631276,0.0006236546,0.0008209712,0.0004195521],"domain_scores_gemma":[0.9973705,0.0001967005,0.0006990238,0.0005674992,0.0009773447,0.0001889357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9736115,0.0008376342,0.0008368224,0.00008983022,0.0009829223,0.000001329412,0.01065967,0.0008657115,0.002366458,0.0001698016,0.002175176,0.007403197],"study_design_scores_gemma":[0.9574728,0.006088682,0.0006094196,0.0001588018,0.0004437264,0.000002097967,0.002746232,0.008056275,0.01482446,0.000009445333,0.009276529,0.0003115236],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787055,0.0005587226,0.001437151,0.001824197,0.003895192,0.01055361,0.0002056669,0.00004752913,0.002772438],"genre_scores_gemma":[0.9794592,0.001005009,0.00128968,0.0006437678,0.002812708,0.004312673,0.0001359928,0.00009298605,0.01024799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01613865,"threshold_uncertainty_score":0.9999248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06666730756198039,"score_gpt":0.3813577451423654,"score_spread":0.314690437580385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}