{"id":"W1498241449","doi":"10.1016/s0091-679x(04)75014-1","title":"Detection of DNA Damage in Individual Cells by Analysis of Histone H2AX Phosphorylation","year":2004,"lang":"en","type":"article","venue":"Methods in cell biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Biology; Histone; Chromatin; DNA damage; Colocalization; DNA; DNA repair; Cell biology; Phosphorylation; DNA replication; Histone H2A; Histone-modifying enzymes; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002474937,0.0003229644,0.0006063444,0.0005568327,0.0003364179,0.0004315949,0.0004319033,0.0005480873,0.001396331],"category_scores_gemma":[0.0001890751,0.0003600425,0.0002886161,0.0004038708,0.0002862596,0.0005181531,0.0005217902,0.001224962,0.0007045849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002297287,"about_ca_system_score_gemma":0.0001171982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003801429,"about_ca_topic_score_gemma":0.0007434545,"domain_scores_codex":[0.9998394,0.000008847393,0.00001186989,0.00006904192,0.0000457193,0.00002494533],"domain_scores_gemma":[0.9997367,0.00008792205,0.00003083465,0.00005660818,0.0000330875,0.0000547824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005766328,0.00001212402,0.0004959088,0.00001776863,0.000006488549,0.00001580979,0.00002332528,0.00003745718,0.997773,0.00004434347,0.00002322695,0.001492798],"study_design_scores_gemma":[0.000009426309,0.0001298393,0.020075,0.000002319234,0.00002812266,0.0001462201,0.00005237495,0.001306617,0.9771876,0.0002031307,0.0008505953,0.000008844497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9135218,0.002009719,0.07854683,0.0001544694,0.00012273,0.0001207532,0.001161558,0.0005397603,0.003822475],"genre_scores_gemma":[0.9469079,0.001577834,0.04405402,0.00020042,0.00007028719,0.0002935663,0.001105795,0.0001538464,0.0056363],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001396331,"threshold_uncertainty_score":0.004671156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0171269952218389,"score_gpt":0.3477004125610157,"score_spread":0.3305734173391768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}