{"id":"W1498383069","doi":"10.1080/15384101.2015.1022060","title":"Unexpected role of CDK4 in a G2/M checkpoint","year":2015,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Biology; G2-M DNA damage checkpoint; CHEK1; Cell cycle checkpoint; Cell biology; Cell Cycle Protein; Checkpoint Kinase 2; Cancer research; Computational biology; Cell cycle; Genetics; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001358854,0.0002746434,0.0006596962,0.0003039398,0.00001073133,0.000006877838,0.0001704507,0.000859507,0.0002975485],"category_scores_gemma":[0.00007086922,0.0002772524,0.0001960248,0.0003428508,0.00007544108,0.00002163249,0.00008127495,0.001626768,0.0002195373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003656536,"about_ca_system_score_gemma":0.0004567173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005082669,"about_ca_topic_score_gemma":0.00002699136,"domain_scores_codex":[0.9982142,0.00006272258,0.0004617574,0.0004131543,0.0004699941,0.0003781349],"domain_scores_gemma":[0.9987851,0.00002575061,0.0002167838,0.0007227959,0.0001475143,0.000102104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009895198,0.0001726701,0.00008600113,0.0004567347,0.00006467385,0.001167988,0.0007586087,0.00003958655,0.1674624,0.000002361418,0.8291169,0.0005731616],"study_design_scores_gemma":[0.002971323,0.000274704,0.000227492,0.0005263999,0.0001729249,0.00006094716,0.0001263448,0.0002810442,0.129892,0.0003145112,0.8647957,0.0003566259],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.3594696,0.02312657,0.00007640497,0.1807753,0.001717384,0.003295903,0.000214367,0.0004342782,0.4308903],"genre_scores_gemma":[0.6381818,0.0003670883,0.002017031,0.3235746,0.00651417,0.0003152228,0.003188819,0.0008916408,0.02494965],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.4059406,"threshold_uncertainty_score":0.999968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01069405859430934,"score_gpt":0.227589776084441,"score_spread":0.2168957174901316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}