{"id":"W1499169356","doi":"10.4049/jimmunol.179.5.2690","title":"Cutting Edge: Peyer’s Patch Plasmacytoid Dendritic Cells (pDCs) Produce Low Levels of Type I Interferons: Possible Role for IL-10, TGFβ, and Prostaglandin E2 in Conditioning a Unique Mucosal pDC Phenotype","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Peyer's patch; Immunology; Biology; Immune system; Spleen; Phenotype; Innate lymphoid cell; CpG Oligodeoxynucleotide; Plasmacytoid dendritic cell; Acquired immune system; Dendritic cell; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001972809,0.0003322313,0.0002932305,0.0001133003,0.0000992726,0.0004397926,0.0001769873,0.0004944878,0.001898584],"category_scores_gemma":[0.0001910017,0.00008601394,0.0001483627,0.0001043187,0.0003557719,0.0002428818,0.0001647123,0.0008478792,0.0006591998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001675474,"about_ca_system_score_gemma":0.0001074791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004558345,"about_ca_topic_score_gemma":0.00007280648,"domain_scores_codex":[0.9998878,0.00001785605,0.000009107393,0.00003208032,0.00002371521,0.00002941268],"domain_scores_gemma":[0.9998487,0.00004552789,0.00002487747,0.00002679317,0.00002104754,0.00003296207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002155613,0.00002518748,0.0007417459,0.0001535926,0.000002703906,0.00009835308,0.00001220736,0.00003444227,0.9903454,0.0002618395,0.0001392318,0.00796964],"study_design_scores_gemma":[0.00006409921,0.0008903246,0.008065047,0.00002377144,0.00003036583,0.001039268,0.00006158819,0.0003812204,0.982619,0.0004686905,0.006352656,0.000003893392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756133,0.008643503,0.008953245,0.001230148,0.0002158918,0.00005441992,0.0003367068,0.0001688246,0.00478403],"genre_scores_gemma":[0.9908156,0.001954875,0.00344469,0.0003877128,0.0001259208,0.00002491559,0.00031024,0.00002099464,0.002914925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001898584,"threshold_uncertainty_score":0.006351411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01380330414652812,"score_gpt":0.2617446309687191,"score_spread":0.247941326822191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}