{"id":"W1499169356","doi":"10.4049/jimmunol.179.5.2690","title":"Cutting Edge: Peyer’s Patch Plasmacytoid Dendritic Cells (pDCs) Produce Low Levels of Type I Interferons: Possible Role for IL-10, TGFβ, and Prostaglandin E2 in Conditioning a Unique Mucosal pDC Phenotype","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Peyer's patch; Immunology; Biology; Immune system; Spleen; Phenotype; Innate lymphoid cell; CpG Oligodeoxynucleotide; Plasmacytoid dendritic cell; Acquired immune system; Dendritic cell; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002581093,0.000258752,0.0006228851,0.0004096325,0.0002401856,0.00001910702,0.0004469611,0.0003139471,0.0002022478],"category_scores_gemma":[0.0005497677,0.0001949805,0.0001075828,0.0002635582,0.0005561071,0.0002085414,0.0001156027,0.0007658252,0.00002075323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009641334,"about_ca_system_score_gemma":0.0003088391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009724754,"about_ca_topic_score_gemma":0.00004358556,"domain_scores_codex":[0.9974486,0.0006838371,0.001045075,0.0001932153,0.00005724638,0.0005720241],"domain_scores_gemma":[0.9970056,0.001530063,0.0007483475,0.0002907852,0.0004055149,0.00001969283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0101914,0.0002232801,0.001045757,0.00006584693,0.0004064112,0.000009655727,0.00401437,0.00001373847,0.9773622,0.0002426582,0.0001707072,0.006253988],"study_design_scores_gemma":[0.004375012,0.002684619,0.009959938,0.0003920541,0.00009365076,0.001010262,0.003486937,0.00001011592,0.9747185,0.0007018167,0.002344659,0.0002224237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9753846,0.02189158,0.0009142247,0.0002898507,0.0008931141,0.0004882633,0.00003735808,0.00001558147,0.00008544949],"genre_scores_gemma":[0.9974671,0.0007732268,0.0003836905,0.00008217859,0.00004970795,0.000007820899,0.00001309485,0.00003549308,0.001187674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02208254,"threshold_uncertainty_score":0.7951075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01380330414652812,"score_gpt":0.2617446309687191,"score_spread":0.247941326822191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}