{"id":"W1499862040","doi":"10.1002/9781118697191.ch1","title":"Introduction to Ligand Design in Medicinal Inorganic Chemistry","year":2014,"lang":"en","type":"other","venue":"","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Limiting; Drug discovery; Nanotechnology; Chemistry; Drug; Combinatorial chemistry; Ligand (biochemistry); Computational biology; Pharmacology; Biochemistry; Materials science; Medicine; Biology; Engineering; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003279134,0.0001933894,0.0004800904,0.0001429129,0.00001076439,0.000009618343,0.00008754051,0.0001872092,0.02937438],"category_scores_gemma":[0.0002483763,0.0001336282,0.0000391789,0.0001290932,0.00003112404,0.000008124066,0.00003062384,0.0001842467,0.0009296854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004405951,"about_ca_system_score_gemma":0.00005776695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001374982,"about_ca_topic_score_gemma":0.00003557173,"domain_scores_codex":[0.9990342,0.00004434042,0.0002148138,0.0003274279,0.00020949,0.0001697044],"domain_scores_gemma":[0.9994289,0.00002479397,0.00005665936,0.0003591258,0.00002087225,0.0001096858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007995449,0.0000287046,0.00003457689,0.0002589459,0.00002982418,0.000003454242,0.00003040092,5.207407e-7,0.1508005,0.00001451215,0.8461083,0.002610298],"study_design_scores_gemma":[0.0002813555,0.0001323822,0.00009239704,0.0003636922,0.00005194853,0.00003916852,0.00002481271,0.00001535319,0.09529058,0.00001563066,0.9035327,0.0001600148],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0009690284,0.001716402,0.004373126,0.005867314,0.000374213,0.0006624208,0.000001618297,0.0001773183,0.9858586],"genre_scores_gemma":[0.005800034,0.0000889336,0.003306208,0.0006376457,0.004524628,0.00002110427,0.00001300563,0.0002122964,0.9853961],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.05742434,"threshold_uncertainty_score":0.9998482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02836749122232294,"score_gpt":0.2476851637023814,"score_spread":0.2193176724800584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}