{"id":"W1500225421","doi":"10.4049/jimmunol.171.1.368","title":"Vulnerability of Human Neurons to T Cell-Mediated Cytotoxicity","year":2003,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":213,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University; Montreal Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale","keywords":"Cytotoxic T cell; CD8; Biology; Cytotoxicity; Cell biology; T cell; Programmed cell death; Neuron; Major histocompatibility complex; Neuroscience; Immunology; Apoptosis; Antigen; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001118918,0.0001744297,0.0001717924,0.0001755921,0.0001562254,0.0003126355,0.00007412026,0.0002607096,0.001271055],"category_scores_gemma":[0.0002107825,0.00006738244,0.000147659,0.0001452817,0.0001360248,0.0001594671,0.0002390378,0.0002188747,0.0004431078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001504075,"about_ca_system_score_gemma":0.0001388285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006738048,"about_ca_topic_score_gemma":0.0004812053,"domain_scores_codex":[0.9998485,0.00002548209,0.00001531738,0.00003747311,0.00003804214,0.00003518306],"domain_scores_gemma":[0.9999055,0.00002292914,0.00001636069,0.00002503098,0.00001941505,0.00001074711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005086962,0.00003434978,0.00569838,0.00009192803,0.00003509843,0.0008103878,0.0001907754,0.0003069813,0.9816226,0.0003004512,0.0001984014,0.01020202],"study_design_scores_gemma":[0.00004483506,0.002019407,0.04986713,0.00006471136,0.0001192358,0.01683296,0.0004281718,0.001297474,0.9157063,0.001214555,0.01238616,0.00001902705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920135,0.003574374,0.001755143,0.00004265583,0.00001244358,0.00001244195,0.0001640437,0.00002697993,0.002398494],"genre_scores_gemma":[0.9968837,0.001414053,0.0003883449,0.00003890397,0.000005668466,0.00001449215,0.0002491901,0.000004043883,0.001001589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001271055,"threshold_uncertainty_score":0.004252136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03531769226267945,"score_gpt":0.2783114618214199,"score_spread":0.2429937695587405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}