{"id":"W1500282449","doi":"10.1096/fasebj.28.1_supplement.1090.11","title":"TRPV4‐associated alterations of Ca <sup>2+</sup> pulsars in a murine model of pulmonary hypertension secondary to heart failure (1090.11)","year":2014,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Pulmonary hypertension; Endothelium; TRPV4; Intracellular; Vasodilation; Homeostasis; Endothelial dysfunction; Internal medicine; Heart failure; Chemistry; Endocrinology; Biology; Medicine; Biochemistry; Transient receptor potential channel; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005743626,0.0006097304,0.0005961574,0.0007445797,0.0002744973,0.0004050238,0.0005141973,0.001154977,0.003698536],"category_scores_gemma":[0.0002161659,0.0003476565,0.0006903418,0.0002590752,0.0006893204,0.0006392423,0.000359062,0.001728229,0.0006684099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003564503,"about_ca_system_score_gemma":0.0003157182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004601376,"about_ca_topic_score_gemma":0.0006332431,"domain_scores_codex":[0.9995204,0.00008082451,0.00005517659,0.0001000945,0.0001038025,0.0001396833],"domain_scores_gemma":[0.9995963,0.00003644344,0.0001507476,0.00004296434,0.00003397016,0.0001395563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001126747,0.0002480856,0.0002286431,0.00007502128,0.000008010376,0.0001937903,0.00003237904,0.00008653708,0.9967315,0.0001076423,0.0001361602,0.001025512],"study_design_scores_gemma":[0.0003987093,0.01073386,0.01434011,0.00005758437,0.00008069361,0.001156184,0.0001698469,0.002232864,0.966895,0.0002015174,0.003708452,0.00002510932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908292,0.0008827311,0.004619923,0.0004498239,0.0001712683,0.0001923817,0.001263115,0.0001979151,0.001393693],"genre_scores_gemma":[0.9846959,0.0009778572,0.004111508,0.0003132951,0.00007296717,0.0006103503,0.001096227,0.00007091882,0.00805099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003698536,"threshold_uncertainty_score":0.01237279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02457322189735236,"score_gpt":0.2674909607621319,"score_spread":0.2429177388647795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}