{"id":"W1500390927","doi":"","title":"Alzheimer amyloid precursor aspartyl proteinase activity in CHAPSO homogenates of Spodoptera frugiperda cells.","year":2005,"lang":"en","type":"article","venue":"PubMed","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Sf9; Presenilin; Spodoptera; Amyloid precursor protein; Proteolysis; Immunoprecipitation; Biochemistry; Peptide; Alpha secretase; Amyloid precursor protein secretase; P3 peptide; Molecular biology; Amyloid beta; Protein precursor; Biology; Chemistry; Alzheimer's disease; Enzyme; Recombinant DNA; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009744611,0.0004397281,0.0002296595,0.0001736673,0.0001778307,0.0002060811,0.0001658004,0.0002091151,0.0006589323],"category_scores_gemma":[0.00007705773,0.000135227,0.0001999311,0.000187117,0.000110323,0.0001294686,0.0001280895,0.0004316,0.0004541531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002808486,"about_ca_system_score_gemma":0.0001583008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002439559,"about_ca_topic_score_gemma":0.003404094,"domain_scores_codex":[0.9999058,0.00001065358,0.00001054152,0.00002365319,0.00002925925,0.00002014879],"domain_scores_gemma":[0.9999392,0.00001316383,0.00001356746,0.000009996611,0.00001191981,0.00001215441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006608178,0.00001450152,0.0001265579,0.00003905341,0.000004983985,0.00005039122,0.00002375826,0.00001654824,0.9991775,0.0000218093,0.00003512453,0.000423603],"study_design_scores_gemma":[0.00002793787,0.000367086,0.01763535,0.00002095309,0.00003158574,0.0004500193,0.00005301605,0.0009596439,0.9736428,0.00003652344,0.006765739,0.000009393099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986035,0.004586098,0.002370756,0.0001808985,0.0001017985,0.00009409617,0.002940071,0.0001051207,0.00358616],"genre_scores_gemma":[0.9679497,0.003974136,0.007173208,0.0001806872,0.00005520315,0.0001445638,0.01165201,0.00004491991,0.008825659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002439559,"threshold_uncertainty_score":0.004850745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01311197744775352,"score_gpt":0.2162256888289708,"score_spread":0.2031137113812173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}