{"id":"W1500390927","doi":"","title":"Alzheimer amyloid precursor aspartyl proteinase activity in CHAPSO homogenates of Spodoptera frugiperda cells.","year":2005,"lang":"en","type":"article","venue":"PubMed","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Sf9; Presenilin; Spodoptera; Amyloid precursor protein; Proteolysis; Immunoprecipitation; Biochemistry; Peptide; Alpha secretase; Amyloid precursor protein secretase; P3 peptide; Molecular biology; Amyloid beta; Protein precursor; Biology; Chemistry; Alzheimer's disease; Enzyme; Recombinant DNA; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001934306,0.0001621776,0.0001749049,0.00006187111,0.00002977156,0.00001308937,0.0001819944,0.000144659,0.00001691636],"category_scores_gemma":[0.00002420282,0.000156197,0.00008343653,0.0001116024,0.00007703947,0.000006926572,0.00006798962,0.00009553757,0.000008361066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001535577,"about_ca_system_score_gemma":0.00003759456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003371482,"about_ca_topic_score_gemma":0.0003996294,"domain_scores_codex":[0.9989133,0.00004744664,0.0001989445,0.0003136402,0.0001317762,0.0003948639],"domain_scores_gemma":[0.9994242,0.000007367344,0.00009526689,0.0003359171,0.00005566118,0.00008158104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003640435,0.0003828699,0.002301273,0.00004243341,0.00008626436,0.000006332443,0.0001142367,0.0001354299,0.8461797,0.00001826019,0.0006663096,0.1497028],"study_design_scores_gemma":[0.0004792431,0.00006306371,0.03816623,0.000005412414,0.0000183058,0.000002711658,0.00001041513,0.00001780838,0.9368505,0.00001574257,0.02419435,0.0001762554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940723,0.002786403,0.00002439547,0.0001436775,0.00007548689,0.000777947,0.00003461366,0.000008313497,0.002076851],"genre_scores_gemma":[0.997718,0.000220573,0.0004258201,0.00008924071,0.0001980577,0.0006465923,0.00002213154,0.00002044635,0.0006590973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1495265,"threshold_uncertainty_score":0.6369528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01311197744775352,"score_gpt":0.2162256888289708,"score_spread":0.2031137113812173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}