{"id":"W1500664144","doi":"10.4049/jimmunol.182.1.319","title":"Genome-Wide Innate Immune Responses in HIV-1-Infected Macrophages Are Preserved Despite Attenuation of the NF-κB Activation Pathway","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Wellcome Trust","keywords":"Biology; Innate immune system; Immune system; TLR2; Cell biology; Immunology; Signal transduction; TLR4; Pattern recognition receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001263863,0.0002169036,0.0002711228,0.0001860142,0.0001552393,0.0003999767,0.000122542,0.000166497,0.0007237938],"category_scores_gemma":[0.000112738,0.0001272484,0.0002214611,0.0001835146,0.0002073973,0.0001414935,0.0002072397,0.0005180881,0.0002345103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001406621,"about_ca_system_score_gemma":0.0001502215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000266196,"about_ca_topic_score_gemma":0.0003442867,"domain_scores_codex":[0.9998646,0.00001468033,0.000009737315,0.00004085644,0.00003628293,0.00003381973],"domain_scores_gemma":[0.9998924,0.00001503722,0.00002876113,0.00002281113,0.00001551548,0.00002552093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003822122,0.000006290803,0.0003694133,0.00001152513,0.000003329998,0.00001038655,0.000008298334,0.00002067064,0.9990921,0.00001358549,0.000005791221,0.0004203948],"study_design_scores_gemma":[0.000007826673,0.00021632,0.06050074,0.000009578171,0.00003066096,0.0003625682,0.0001146231,0.0007396505,0.9365467,0.000130386,0.001334184,0.000006690104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965793,0.001241726,0.001260524,0.00004174766,0.000006617129,0.000007817262,0.0004721161,0.0000397499,0.0003503828],"genre_scores_gemma":[0.9963956,0.0005423318,0.001107382,0.00005444603,0.000005631892,0.00002354456,0.0009657884,0.00001416606,0.000891116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007237938,"threshold_uncertainty_score":0.00242126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01579229079994623,"score_gpt":0.2505537998565234,"score_spread":0.2347615090565772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}