{"id":"W1501639205","doi":"10.1371/journal.ppat.1005107","title":"Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Hospital for Sick Children; University of Calgary; Child and Family Research Institute; SickKids Foundation; University of Toronto","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; CH.I.L.D. Foundation; Canadian Institutes of Health Research; Hospital for Sick Children; Keio University","keywords":"Citrobacter rodentium; Microbiology; Biology; Hexose; Pathogenesis; PEP group translocation; In vivo; Heptose; Bacteria; Pathogen; Mucus; Biochemistry; Escherichia coli; Mutant; Enzyme; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014553,0.0001107138,0.0001915069,0.00003500519,0.00002360955,0.000002452229,0.0000609534,0.0001259177,0.00001140403],"category_scores_gemma":[0.00004472415,0.0001010696,0.00003810525,0.00009100817,0.00007551695,0.000003822021,0.0000166549,0.00004600624,4.053677e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008610542,"about_ca_system_score_gemma":0.0001889184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002511473,"about_ca_topic_score_gemma":0.00001428494,"domain_scores_codex":[0.9993064,0.00004972037,0.0002331315,0.0001996749,0.00008075988,0.0001303407],"domain_scores_gemma":[0.9994376,0.000006719111,0.0001207705,0.0001154162,0.0002194648,0.0001000483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004051495,0.0001567407,0.00662594,0.00008947735,0.00003176554,0.000002706729,0.001039264,0.000004450545,0.9907628,0.000005439307,0.00001286957,0.000863437],"study_design_scores_gemma":[0.0006799019,0.000887874,0.01121221,0.00005950676,0.00006175206,0.00001078836,0.0001244736,0.00009168037,0.9864908,0.000023046,0.0002519509,0.0001059621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988037,0.0003266375,0.0002592498,0.00002723469,0.00003245581,0.0002621761,0.0002069774,0.000007258669,0.00007430477],"genre_scores_gemma":[0.9978206,0.00009239434,0.001525428,0.00001027867,0.00003463403,0.000006986725,0.000475234,0.00001572876,0.00001867548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004586271,"threshold_uncertainty_score":0.4121498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01574597966680867,"score_gpt":0.2330670248336172,"score_spread":0.2173210451668085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}