{"id":"W1501762129","doi":"10.1016/s0079-6123(08)62132-9","title":"Long-term behavioral and neuroendocrine adaptations to adverse early experience","year":2000,"lang":"en","type":"review","venue":"Progress in brain research","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":713,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute of Mental Health","keywords":"Internal medicine; Endocrinology; Granule cell; Glucocorticoid receptor; Biology; Neurogenesis; Synaptogenesis; Neurotrophic factors; Dentate gyrus; Hippocampal formation; Neuroscience; Glucocorticoid; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2679506685304129,"score_gpt":0.513078389580363,"score_spread":0.2451277210499501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."},"direct_labels":[],"classifier":{"requested":true,"available":true,"version":"metacan-v1-d91a1de5be90","frame_rows_covered":4299418,"decision_targets":["metaresearch","metaepi_narrow","metaepi_broad","bibliometrics","sts","scholarly_communication","open_science","research_integrity","randomized_trial","nonrandomized_trial","observational","systematic_review","meta_analysis","case_report","qualitative","simulation_or_modeling","bench_or_experimental","theoretical_or_conceptual","not_applicable"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame.","warning":null},"prediction":{"classifier_version":"metacan-v1-d91a1de5be90","candidate_union":["observational","not_applicable"],"consensus_intersection":["observational"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"scores":{"codex":{"metaresearch":0.0007934691386282139,"metaepi_narrow":0.000015259021896696422,"metaepi_broad":0.00012207217517357137,"bibliometrics":0.00018310826276035706,"sts":0.000030518043793392844,"scholarly_communication":0.0011749446860456244,"open_science":0.00019836728465705348,"research_integrity":0.00044251163500419623,"randomized_trial":0.00006103608758678569,"nonrandomized_trial":0.000289921416037232,"observational":0.026581216144045166,"systematic_review":0.0023956664377813384,"meta_analysis":0.00009155413138017853,"case_report":0.0008087281605249104,"qualitative":0.00025940337224383917,"simulation_or_modeling":0.000045777065690089265,"bench_or_experimental":0.00009155413138017853,"theoretical_or_conceptual":0.00044251163500419623,"not_applicable":0,"design_other":0.9951476310368506},"gemma":{"metaresearch":0.00015259021896696422,"metaepi_narrow":0.000015259021896696422,"metaepi_broad":0.001052872510872053,"bibliometrics":0.00015259021896696422,"sts":0.00025940337224383917,"scholarly_communication":0.00006103608758678569,"open_science":0.00007629510948348211,"research_integrity":0.0008087281605249104,"randomized_trial":0.00006103608758678569,"nonrandomized_trial":0.0003662165255207141,"observational":0.19385061417563135,"systematic_review":0.005951018539711604,"meta_analysis":0.00007629510948348211,"case_report":0.0004119935912108034,"qualitative":0.0003356984817273213,"simulation_or_modeling":0.000015259021896696422,"bench_or_experimental":0.000030518043793392844,"theoretical_or_conceptual":0.00006103608758678569,"not_applicable":0.6085450522621499}},"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame."}}