{"id":"W1502111999","doi":"10.1111/j.1742-4658.2009.06880.x","title":"Kinetic and mechanistic characterization of <i>Mycobacterium tuberculosis</i> glutamyl–tRNA synthetase and determination of its oligomeric structure in solution","year":2009,"lang":"en","type":"article","venue":"FEBS Journal","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fondazione Cariplo","keywords":"Transfer RNA; Enzyme; Biochemistry; Escherichia coli; Biology; Proteolysis; Molecular biology; RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001733309,0.0001105357,0.0001735521,0.00009900957,0.00003933366,0.00001799893,0.00006043499,0.0001125064,0.00001453775],"category_scores_gemma":[0.00006526464,0.0001021952,0.00003126842,0.00007428013,0.00002475349,0.00001529773,0.0000206299,0.00006746897,1.716506e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008857063,"about_ca_system_score_gemma":0.00002239569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001744972,"about_ca_topic_score_gemma":0.000002102409,"domain_scores_codex":[0.9992498,0.0000889868,0.0002854435,0.0001431637,0.0001075487,0.0001251159],"domain_scores_gemma":[0.9995313,0.000007640462,0.0002424157,0.00008916563,0.00007494907,0.00005457625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008380961,0.00002429263,0.0002029198,0.00004502823,0.00000672271,0.000002475771,0.00004233228,0.000001675275,0.9724095,0.0000527483,9.164299e-7,0.02712756],"study_design_scores_gemma":[0.0003421237,0.0004230539,0.0263135,0.0001037633,0.00003148265,0.0002443197,0.0000101575,0.0002879092,0.9715112,0.0005599146,0.00006756647,0.0001049879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917657,0.000669021,0.007224483,0.00007663829,0.00008562383,0.0001251712,0.0000341464,0.000001968019,0.00001727516],"genre_scores_gemma":[0.9973053,0.0015209,0.001010203,0.00003982786,0.00007718394,0.000001731095,0.0000266479,0.000008195064,0.00001006086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02702257,"threshold_uncertainty_score":0.4167401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0055580172672957,"score_gpt":0.2168539641459418,"score_spread":0.2112959468786461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}