{"id":"W1503263434","doi":"10.5772/22827","title":"Natural Killer Cells from HIV Infected Slow Progressors Who Carry the Protective HLA-B*27 Allele and Inhibitory KIR3DL1 Receptors Have Elevated Poly-Functional Potential Compared to Bw6 Homozygotes","year":2011,"lang":"en","type":"book-chapter","venue":"InTech eBooks","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; St. Paul's Hospital; Maple Leaf Medical Clinic; Royal Victoria Hospital; McGill University; Centre Hospitalier de l’Université de Montréal; Clinique Paro Excellence; Royal Victoria Regional Health Centre; McGill University Health Centre","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Allele; Human leukocyte antigen; Human immunodeficiency virus (HIV); Receptor; Inhibitory postsynaptic potential; Immunology; Biology; Virology; Gene; Genetics; Antigen; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007786561,0.0002559581,0.000230176,0.000204303,0.0001449229,0.0004169394,0.0001737057,0.0002636802,0.006257451],"category_scores_gemma":[0.0001010542,0.0001131666,0.0001881625,0.0002283379,0.0001530569,0.0002794155,0.0002825387,0.0006289579,0.002517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001025209,"about_ca_system_score_gemma":0.00006533648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003474987,"about_ca_topic_score_gemma":0.0003277386,"domain_scores_codex":[0.9999288,0.0000082053,0.000006356415,0.00001364686,0.00001923071,0.00002376767],"domain_scores_gemma":[0.9999278,0.00001933651,0.00001183838,0.000007593721,0.000009130629,0.00002430672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006717334,0.00005276935,0.002964826,0.00008370687,0.00001568065,0.0005601126,0.0001386657,0.00005195832,0.96788,0.0003598022,0.0007898689,0.02643087],"study_design_scores_gemma":[0.0003100175,0.004473744,0.3622746,0.0001427265,0.0001955482,0.02473923,0.001378019,0.0009912754,0.540246,0.002870648,0.0622767,0.0001015809],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97351,0.00700899,0.002024338,0.00019478,0.0001028449,0.00003154868,0.0007793754,0.0001047828,0.01624335],"genre_scores_gemma":[0.9379415,0.004340951,0.001577916,0.0002592017,0.00006329625,0.00005937439,0.002676989,0.00006948299,0.05301128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006257451,"threshold_uncertainty_score":0.02093321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01186875045624287,"score_gpt":0.2015679120617859,"score_spread":0.1896991616055431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}