{"id":"W1503263434","doi":"10.5772/22827","title":"Natural Killer Cells from HIV Infected Slow Progressors Who Carry the Protective HLA-B*27 Allele and Inhibitory KIR3DL1 Receptors Have Elevated Poly-Functional Potential Compared to Bw6 Homozygotes","year":2011,"lang":"en","type":"book-chapter","venue":"InTech eBooks","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; St. Paul's Hospital; Maple Leaf Medical Clinic; Royal Victoria Hospital; McGill University; Centre Hospitalier de l’Université de Montréal; Clinique Paro Excellence; Royal Victoria Regional Health Centre; McGill University Health Centre","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Allele; Human leukocyte antigen; Human immunodeficiency virus (HIV); Receptor; Inhibitory postsynaptic potential; Immunology; Biology; Virology; Gene; Genetics; Antigen; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001916101,0.0008152492,0.0007629484,0.000422472,0.0005028695,0.00009242241,0.0003524563,0.001203854,0.003650055],"category_scores_gemma":[0.00007222885,0.0006399411,0.0003478501,0.00003796912,0.0007282658,0.0001176319,0.0003531746,0.002508857,0.00133068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002357122,"about_ca_system_score_gemma":0.0001426492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007732298,"about_ca_topic_score_gemma":0.0002003535,"domain_scores_codex":[0.9973868,0.0002523198,0.0007444241,0.0009192008,0.0001623446,0.0005349562],"domain_scores_gemma":[0.998091,0.0001765842,0.0005247496,0.0005755682,0.0005558768,0.00007622049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003468673,0.0001015656,0.0000386531,0.00002950901,0.002084398,0.0000201756,0.002561119,0.000001393846,0.8661435,0.0003181476,0.1176206,0.007612243],"study_design_scores_gemma":[0.001253912,0.000371281,0.0002672379,0.0003514675,0.0002119499,0.00009147147,0.0003272059,0.000005785333,0.4477453,0.0006093257,0.5480345,0.0007305924],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.2154152,0.02777121,0.008049013,0.002361325,0.2491111,0.02802614,0.0009323881,0.004835145,0.4634985],"genre_scores_gemma":[0.3688976,0.00003287511,0.00003913876,0.0003552239,0.0003175776,0.0001718462,0.0008109739,0.0001191007,0.6292557],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.4304139,"threshold_uncertainty_score":0.9997924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01186875045624287,"score_gpt":0.2015679120617859,"score_spread":0.1896991616055431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}