{"id":"W1503357796","doi":"10.1016/s0070-2153(06)77004-1","title":"Mitochondrial DNA and the Mammalian Oocyte","year":2007,"lang":"en","type":"review","venue":"Current topics in developmental biology/Current Topics in Developmental Biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":283,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Heteroplasmy; Biology; Mitochondrial DNA; Genetics; Oocyte; Mitochondrion; Somatic cell; Germline; Germ cell; Zygote; Cell biology; Population; Mitochondrial biogenesis; Embryo; Gene; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005293415,0.0005972796,0.0009444765,0.001282119,0.0003622114,0.0010314,0.001060969,0.001717882,0.002365041],"category_scores_gemma":[0.000403849,0.0002770846,0.0001907559,0.001333783,0.001199628,0.001720812,0.0007395829,0.001544026,0.001985378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001045839,"about_ca_system_score_gemma":0.001086442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001162811,"about_ca_topic_score_gemma":0.002392809,"domain_scores_codex":[0.9998906,0.00001488203,0.0000109789,0.00002385153,0.0000483793,0.0000112824],"domain_scores_gemma":[0.9998283,0.00006055549,0.00002880068,0.000007370593,0.00004475689,0.00003008534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001580362,0.00003972107,0.0002548855,0.006190821,0.00003776249,0.0007340594,0.000107339,0.0005189934,0.01197331,0.01784533,0.03088287,0.9312568],"study_design_scores_gemma":[0.0000209562,0.00005143687,0.0006664476,0.0008106707,0.00002762962,0.001306838,0.0001165476,0.00005342409,0.001712484,0.005793663,0.9894248,0.0000150511],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002579339,0.9965964,0.0003118704,0.0006580795,0.000458148,0.000003610856,0.00001009952,0.000007339233,0.001696601],"genre_scores_gemma":[0.001481648,0.9961163,0.0002650317,0.0002876791,0.0004627946,0.000006675261,0.0000228017,0.000001135708,0.001356022],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002365041,"threshold_uncertainty_score":0.007911861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.080254119768384,"score_gpt":0.3483694660382208,"score_spread":0.2681153462698368,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}