{"id":"W1503393355","doi":"10.1109/sensor.2005.1496394","title":"Mems-based sonoporation devices for intratumoral gene therapy","year":2005,"lang":"en","type":"article","venue":"","topic":"Microfluidic and Bio-sensing Technologies","field":"Engineering","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Sonoporation; Transfection; Umbilical vein; Genetic enhancement; Oligonucleotide; Cavitation; In vitro; Human umbilical vein endothelial cell; Gene delivery; Biomedical engineering; Molecular biology; Chemistry; Cancer research; Materials science; Gene; Medicine; Biology; Microbubbles; Ultrasound; Biochemistry; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005769588,0.00008318056,0.00007554941,0.00004138341,0.00003582875,0.00002748952,0.00007172971,0.00007098875,0.00003189112],"category_scores_gemma":[0.000004524627,0.00006568531,0.00002860488,0.00006017335,0.00001984134,0.00006177714,0.000004372118,0.00004019187,0.00001524645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002382565,"about_ca_system_score_gemma":0.0000103779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004176654,"about_ca_topic_score_gemma":0.00002756614,"domain_scores_codex":[0.9996486,0.000002174805,0.0001011096,0.00008111857,0.00003820228,0.000128798],"domain_scores_gemma":[0.9998266,0.00001336654,0.00001182022,0.0001116035,0.00002285327,0.00001371821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000124689,0.00001718711,0.00009831175,0.00001266722,0.00001308837,3.986002e-7,0.00002116706,0.0008856693,0.8093615,0.0005227775,0.03691663,0.1521381],"study_design_scores_gemma":[0.0002401648,0.00003488236,0.00009953931,0.000002991659,0.000002457392,8.996763e-7,0.00002894629,0.02741377,0.8908096,0.0001360689,0.08113107,0.00009959369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8044312,0.002547847,0.1875128,0.00184138,0.0001587238,0.000279151,0.000007402783,0.002206638,0.001014829],"genre_scores_gemma":[0.9521528,0.0001420105,0.04724225,0.0002416363,0.00009860232,0.000009804725,0.00002078733,0.00001316077,0.00007887222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1520385,"threshold_uncertainty_score":0.2678569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02054627057761543,"score_gpt":0.2270053434976449,"score_spread":0.2064590729200295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}