{"id":"W1503975979","doi":"","title":"Thrombospondin-1 receptor mediates autophagy of RAS-expressing cancer cells and triggers tumour growth inhibition.","year":2013,"lang":"en","type":"article","venue":"PubMed","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"","keywords":"CD47; Autophagy; Thrombospondin 1; Biology; Cancer cell; Angiogenesis; Acridine orange; Cancer research; Receptor; Apoptosis; Cell culture; Viability assay; Cell biology; Cell growth; Molecular biology; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008988498,0.0002699147,0.0002251839,0.0001453282,0.0001280901,0.0001419734,0.0001301575,0.0002050959,0.0009243489],"category_scores_gemma":[0.00006070614,0.0000825828,0.0002334717,0.0001089565,0.0001730049,0.0001213279,0.0001173571,0.0003559647,0.0004883154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002358903,"about_ca_system_score_gemma":0.000157876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002829331,"about_ca_topic_score_gemma":0.0005910416,"domain_scores_codex":[0.9999181,0.00001624953,0.00000708392,0.00001329452,0.00002481153,0.00002052259],"domain_scores_gemma":[0.9999435,0.000009611112,0.00001897728,0.000008768133,0.000005877974,0.00001337581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001900355,0.00003637619,0.0001430893,0.00005035478,0.000005233824,0.00006847623,0.00001139774,0.00006168707,0.9983379,0.00007410672,0.00006833277,0.0009530439],"study_design_scores_gemma":[0.00002527454,0.0004651427,0.003433827,0.000004760113,0.00001181815,0.0004275158,0.00001654953,0.001089639,0.9924891,0.00003985032,0.001993632,0.000002930222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963874,0.001145792,0.0006775561,0.0000822746,0.00001699601,0.00001733331,0.0003055118,0.0000551648,0.001312165],"genre_scores_gemma":[0.9960719,0.0007542764,0.000723972,0.00002783679,0.000007357707,0.00003201613,0.0005617205,0.000008724303,0.001812055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009243489,"threshold_uncertainty_score":0.003092229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01138562425256434,"score_gpt":0.2191121687222215,"score_spread":0.2077265444696572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}