{"id":"W1504162296","doi":"10.1002/9780470372531.ch3","title":"Drug‐Associated Mitochondrial Toxicity","year":2008,"lang":"en","type":"other","venue":"","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Steatohepatitis; Steatosis; Endogeny; Oxidative stress; Drug; Toxicity; Mitochondrial toxicity; Liver toxicity; Pharmacology; Chemistry; Liver injury; Mitochondrion; Fatty liver; Biology; Biochemistry; Medicine; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001133105,0.0004736863,0.0003348224,0.0006882295,0.0002477837,0.000547074,0.0003543416,0.0004634594,0.06759395],"category_scores_gemma":[0.0001654301,0.0001201085,0.0003397094,0.0005454355,0.0001100126,0.0004187488,0.0005246056,0.0004605699,0.01631802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005407453,"about_ca_system_score_gemma":0.0003361795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000709237,"about_ca_topic_score_gemma":0.00180032,"domain_scores_codex":[0.9999049,0.000007882331,0.000006304813,0.00001270308,0.00005502506,0.00001319083],"domain_scores_gemma":[0.9999287,0.00001142178,0.00001251149,0.000008561913,0.00002815,0.0000106678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000224522,0.0002868131,0.0007314204,0.002677423,0.00004097359,0.00122828,0.00006354872,0.0004752055,0.1148191,0.007993718,0.2065325,0.6649265],"study_design_scores_gemma":[0.00002026393,0.0002022579,0.005424367,0.0004518928,0.00003208561,0.002618135,0.00003745085,0.000225536,0.05730538,0.001654032,0.9320137,0.00001501117],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.03123338,0.2982302,0.01302763,0.007180545,0.006093637,0.0005471568,0.009147467,0.002267383,0.6322727],"genre_scores_gemma":[0.04732022,0.2578683,0.005466318,0.002804347,0.001258497,0.0001604291,0.005340537,0.0002054507,0.6795759],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.06759395,"threshold_uncertainty_score":0.2261243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005455787347097223,"score_gpt":0.2186501023577668,"score_spread":0.2131943150106696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}