{"id":"W1504597909","doi":"10.1002/9781118433034.ch9","title":"Meiotic Recombination‐Based Genome Shuffling of <i>Saccharomyces Cerevisiae</i> and <i>Schefferomyces Stiptis</i> for Increased Inhibitor Tolerance to Lignocellulosic Substrate Toxicity","year":2012,"lang":"en","type":"other","venue":"","topic":"Biofuel production and bioconversion","field":"Engineering","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"","keywords":"Saccharomyces cerevisiae; DNA shuffling; Shuffling; Strain (injury); Recombination; Genetics; Homologous recombination; Meiosis; Biology; Yeast; Computational biology; Biotechnology; Chemistry; Directed evolution; Gene; Computer science; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001887488,0.0004298253,0.0002610352,0.0004434057,0.0001669836,0.000359556,0.0002797057,0.000179635,0.002828452],"category_scores_gemma":[0.0001374053,0.000156668,0.0004251528,0.0004834632,0.00009235637,0.0001718961,0.000248096,0.0005021613,0.001199292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002162511,"about_ca_system_score_gemma":0.0003283657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009431042,"about_ca_topic_score_gemma":0.00236665,"domain_scores_codex":[0.9998595,0.00001709794,0.00001770004,0.00002720973,0.00005848391,0.00002003345],"domain_scores_gemma":[0.9999527,0.000008881425,0.000009629696,0.00001221986,0.000009917966,0.000006661078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009722435,0.00004769656,0.0001925409,0.00009186048,0.000008661298,0.00008109705,0.00003068642,0.0002880739,0.9784824,0.0004807541,0.0005944442,0.01960447],"study_design_scores_gemma":[0.000008308465,0.0000808175,0.001118433,0.000006875903,0.00001797359,0.0001332718,0.00002012637,0.0004073108,0.983195,0.00005847729,0.01494481,0.000008578002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8873684,0.005237561,0.06436212,0.0004198847,0.0003858149,0.0004081162,0.004772794,0.002370204,0.03467515],"genre_scores_gemma":[0.8375587,0.009457834,0.07302891,0.0002169681,0.00005005289,0.0002363552,0.01856454,0.001397396,0.05948928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002828452,"threshold_uncertainty_score":0.009462118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01191878415130598,"score_gpt":0.2052759898985246,"score_spread":0.1933572057472186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}