{"id":"W1505086866","doi":"10.1111/j.1574-695x.2010.00693.x","title":"Cellular responses of A549 alveolar epithelial cells to serially collected<i>Pseudomonas aeruginosa</i>from cystic fibrosis patients at different stages of pulmonary infection","year":2010,"lang":"en","type":"article","venue":"FEMS Immunology & Medical Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Lakehead University","funders":"","keywords":"Pseudomonas aeruginosa; Microbiology; Biology; Proinflammatory cytokine; Cystic fibrosis; Virulence; Pyocyanin; A549 cell; Immunology; Cytokine; Apoptosis; Inflammation; Bacteria; Quorum sensing; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002362329,0.0003439615,0.0006564586,0.0001401805,0.0001233028,0.000007267431,0.0003642289,0.001173166,0.0003550231],"category_scores_gemma":[0.0005978996,0.0003011076,0.0002004954,0.0001399452,0.0007644096,0.000005409435,0.00061208,0.0003585643,0.00002481741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003121393,"about_ca_system_score_gemma":0.0001440117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006426613,"about_ca_topic_score_gemma":0.0004466538,"domain_scores_codex":[0.9975278,0.0004987197,0.0007466885,0.0006128016,0.0001152611,0.0004987537],"domain_scores_gemma":[0.9985163,0.0001959413,0.0003622278,0.0005539103,0.0002156047,0.0001559934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00236416,0.000366296,0.01133757,0.00002362461,0.0002183547,0.000008170861,0.00006626668,0.000001065769,0.9838719,0.000007776631,0.0005106842,0.001224151],"study_design_scores_gemma":[0.001108739,0.001116862,0.05892448,0.00003796392,0.00005573509,0.00003191265,0.00000855134,0.000001733284,0.9259111,0.000007827812,0.01254064,0.0002545077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949274,0.0002749104,0.00007652731,0.0001586308,0.003096645,0.0003600061,0.001064621,0.00002005847,0.00002119118],"genre_scores_gemma":[0.9972712,0.0002032273,0.0004288988,0.0001732125,0.0002701025,0.00001377657,0.001420106,0.00003598301,0.0001835354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05796083,"threshold_uncertainty_score":0.9999441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003722606371371804,"score_gpt":0.200623006989846,"score_spread":0.1969004006184742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}