{"id":"W1505255102","doi":"10.1089/dia.2013.0363","title":"OpT2mise: A Randomized Controlled Trial to Compare Insulin Pump Therapy with Multiple Daily Injections in the Treatment of Type 2 Diabetes—Research Design and Methods","year":2014,"lang":"en","type":"article","venue":"Diabetes Technology & Therapeutics","topic":"Diabetes Management and Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"LMC Diabetes & Endocrinology (Canada)","funders":"Novo Nordisk; Medtronic Europe; Eli Lilly and Company","keywords":"Medicine; Hypoglycemia; Glycemic; Regimen; Randomized controlled trial; Glycated hemoglobin; Type 1 diabetes; Postprandial; Insulin; Diabetes mellitus; Crossover study; Clinical endpoint; Type 2 diabetes; Insulin pump; Internal medicine; Pediatrics; Endocrinology; Placebo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005808482,0.002710815,0.00557194,0.001066716,0.0005669097,0.001701885,0.001397567,0.002538845,0.01147572],"category_scores_gemma":[0.005502178,0.0009959314,0.003433046,0.0008049177,0.001529347,0.002171231,0.001151444,0.002588826,0.0009973381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001071525,"about_ca_system_score_gemma":0.001805471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006405236,"about_ca_topic_score_gemma":0.0008751983,"domain_scores_codex":[0.9950287,0.003413753,0.0003215862,0.0005840841,0.0003042656,0.0003477042],"domain_scores_gemma":[0.9971448,0.001157732,0.0006660318,0.0002584283,0.0001831537,0.0005898493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9929935,0.002017617,0.0002235377,0.0003307977,0.0007906809,0.0000107833,0.00000769366,0.0001550771,0.0001855621,0.000122723,0.0001789873,0.002982906],"study_design_scores_gemma":[0.9803499,0.01814397,0.0003616938,0.00001794847,0.0003479819,0.000007150758,0.000005780173,0.000401978,0.00005260622,0.0001226457,0.0001814083,0.000006893521],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.9271798,0.009295763,0.006300926,0.002006575,0.003746317,0.04279724,0.003420555,0.0005575492,0.004695268],"genre_scores_gemma":[0.8893304,0.003437599,0.01473785,0.002792848,0.002156928,0.07819265,0.002778081,0.00008035762,0.006493316],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.01147572,"threshold_uncertainty_score":0.0383901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07139719660732402,"score_gpt":0.3979258719146193,"score_spread":0.3265286753072953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}