{"id":"W1506042288","doi":"10.1002/pbc.25133","title":"Efficacy of CPX‐351, (cytarabine:daunorubicin) liposome injection, against acute lymphoblastic leukemia (ALL) xenograft models of the Pediatric Preclinical Testing Program","year":2014,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Celator Pharmaceuticals (Canada)","funders":"National Cancer Institute; Celator Pharmaceuticals; University of New South Wales","keywords":"Daunorubicin; Cytarabine; Medicine; Pharmacology; Cmax; Pharmacokinetics; Leukemia; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004722635,0.0007240325,0.0003739739,0.0004249233,0.0001628095,0.0003776701,0.0003017589,0.0003364376,0.001215647],"category_scores_gemma":[0.0001501887,0.0001752242,0.0002342866,0.0002376072,0.0003274372,0.0003904862,0.0001204428,0.0009743,0.0002622093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006320556,"about_ca_system_score_gemma":0.000419781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00136955,"about_ca_topic_score_gemma":0.001593481,"domain_scores_codex":[0.9998249,0.00004499464,0.00001305477,0.00003820682,0.00004299168,0.0000357112],"domain_scores_gemma":[0.9998173,0.00005231086,0.00005183941,0.00002036124,0.00001782981,0.00004036576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001729866,0.0009595143,0.00036177,0.00008771577,0.00002860562,0.0000395043,0.00006089846,0.000690354,0.9907458,0.0001655918,0.000184694,0.004945671],"study_design_scores_gemma":[0.0001854871,0.009040892,0.001826373,0.000004801819,0.0000389169,0.0001164969,0.00001454485,0.001546577,0.9863154,0.00001606082,0.0008894319,0.00000492316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995639,0.0008373504,0.001870222,0.00007767335,0.00002238806,0.0001885779,0.0004560734,0.0001554157,0.0007531835],"genre_scores_gemma":[0.995346,0.0006713732,0.002153032,0.0000199496,0.000007883612,0.00009631245,0.0006602221,0.00002255663,0.001022632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00136955,"threshold_uncertainty_score":0.004585981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02999631826602936,"score_gpt":0.313768197906212,"score_spread":0.2837718796401826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}