{"id":"W1506859052","doi":"10.1158/1538-7445.am2014-807","title":"Abstract 807: Selamectin and ivermectin are small molecule inhibitors that interfere with Sin3A-PAH2 function and exert anti-tumor activity in triple-negative breast cancer","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Chemistry; Epigenetics; In vivo; Cell biology; Cancer research; Biology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008979281,0.00042663,0.0003712129,0.0003027932,0.00007723525,0.0001921789,0.0002080411,0.0001609511,0.002225002],"category_scores_gemma":[0.00007428903,0.0000791034,0.000294085,0.0001912522,0.0001056889,0.0001117038,0.0001551836,0.0002731872,0.0003978801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002056624,"about_ca_system_score_gemma":0.0001321888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004079772,"about_ca_topic_score_gemma":0.0008123887,"domain_scores_codex":[0.9999572,0.000006974619,0.000003007968,0.000007128757,0.00001670357,0.000009000093],"domain_scores_gemma":[0.9999778,0.000003906142,0.000006597895,0.000001466531,0.000004322345,0.000005954929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004789793,0.0001876945,0.0007197713,0.0002237057,0.00006836616,0.0001234382,0.00001161994,0.00186538,0.9754546,0.0001804675,0.0005141732,0.02017188],"study_design_scores_gemma":[0.0003321192,0.003081919,0.00544649,0.00002805964,0.0001728214,0.0005203169,0.00002325012,0.008860661,0.9714986,0.0001017106,0.009916515,0.00001743256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853199,0.004773737,0.003609242,0.0001710317,0.00004367,0.0001387275,0.001262053,0.0002004963,0.004481063],"genre_scores_gemma":[0.9886424,0.002409328,0.002577516,0.0001311505,0.0000113988,0.00005846879,0.001998794,0.00002100413,0.004149911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002225002,"threshold_uncertainty_score":0.007443428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03266877192381467,"score_gpt":0.3172750711266548,"score_spread":0.2846062992028401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}