{"id":"W1507228714","doi":"10.1089/027245700315743","title":"Construction and Characterization of a Novel Recombinant Single-Chain Variable Fragment Antibody Against Western Equine Encephalitis Virus","year":2000,"lang":"en","type":"article","venue":"Hybridoma","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Department of National Defence; Defence Research and Development Canada","funders":"U.S. Army Medical Research Institute of Infectious Diseases; Army Research Institute for the Behavioral and Social Sciences; Natural Sciences and Engineering Research Council of Canada","keywords":"Recombinant DNA; Antibody; Phage display; Molecular biology; Immunoglobulin light chain; Virology; Monoclonal antibody; Biology; Affinity chromatography; Single-chain variable fragment; Virus; Chemistry; Biochemistry; Enzyme; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001647441,0.0002526163,0.0003050684,0.0001685058,0.0001318976,0.0003055271,0.0002215727,0.0002251846,0.0006038728],"category_scores_gemma":[0.0002081753,0.0001037425,0.0002258529,0.0001531702,0.0001175689,0.0001693605,0.0001205874,0.0003748814,0.0003269248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003556435,"about_ca_system_score_gemma":0.000148184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007911228,"about_ca_topic_score_gemma":0.0006681386,"domain_scores_codex":[0.999886,0.00001301904,0.000009728056,0.00002262419,0.00004341349,0.00002519178],"domain_scores_gemma":[0.9998989,0.00001696206,0.00001841151,0.00001114829,0.00002505057,0.00002956857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001917592,0.00002232975,0.0002057131,0.00001481485,0.000003423516,0.00005623139,0.00001113013,0.00007566638,0.9982964,0.00005597206,0.00002716399,0.001211951],"study_design_scores_gemma":[0.00002664774,0.0003859016,0.0063993,0.000006644492,0.00003355393,0.0008752882,0.00003423021,0.002691552,0.9811205,0.00004871687,0.008369524,0.000008015772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850951,0.0006449887,0.01269835,0.00007667575,0.00002494299,0.00006017918,0.0003178252,0.000045004,0.001036952],"genre_scores_gemma":[0.9738531,0.0006468031,0.01959685,0.00008388366,0.00001756008,0.00004754031,0.002880645,0.0000232845,0.002850377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007911228,"threshold_uncertainty_score":0.002580404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02426992971611104,"score_gpt":0.2812705837562813,"score_spread":0.2570006540401703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}