{"id":"W1507515137","doi":"10.1038/81814","title":"Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization","year":2000,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":555,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"School of Medicine, Stanford University; Medical Research Council Canada; Heart and Stroke Foundation of Canada; National Institute of Neurological Disorders and Stroke; Medical Research Council; Korea Science and Engineering Foundation; Johns Hopkins University; Howard Hughes Medical Institute","keywords":"AMPA receptor; Internalization; Silent synapse; Long-term depression; Cell biology; Dynamin; Biology; Ion channel linked receptors; Postsynaptic potential; Neurotransmission; Neuroscience; SGK1; Synaptic plasticity; Glutamate receptor; Receptor; Chemistry; Endocytosis; Biochemistry; Phosphorylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001121137,0.0005564067,0.001315865,0.001056355,0.0006799173,0.003394995,0.00132291,0.001686066,0.00119425],"category_scores_gemma":[0.001680635,0.0007097722,0.001430524,0.0004236281,0.001040165,0.002918283,0.001698661,0.002813488,0.0008886924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001602288,"about_ca_system_score_gemma":0.0008403707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001094161,"about_ca_topic_score_gemma":0.001134543,"domain_scores_codex":[0.9989781,0.00009155997,0.0001050162,0.0001490267,0.000324024,0.0003521822],"domain_scores_gemma":[0.999096,0.0001770623,0.000119087,0.0001476993,0.0003223682,0.0001377324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009520687,0.00007310342,0.001428433,0.0002138492,0.00006708674,0.0002750826,0.0005461001,0.0004498717,0.9580845,0.02722161,0.0002807056,0.01040771],"study_design_scores_gemma":[0.000209162,0.0007259008,0.1038497,0.0002370665,0.0002796879,0.00530621,0.002173663,0.0101163,0.8402466,0.02651467,0.01010868,0.0002323608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9329647,0.01479403,0.0348252,0.001017262,0.0002260171,0.0001877203,0.0007232364,0.0003129324,0.014949],"genre_scores_gemma":[0.9694256,0.006583008,0.01780958,0.0003399838,0.00006747276,0.0002314934,0.00105709,0.0001265604,0.004359216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003394995,"threshold_uncertainty_score":0.01162547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02534506049770316,"score_gpt":0.303838937405263,"score_spread":0.2784938769075598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}