{"id":"W1507515137","doi":"10.1038/81814","title":"Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization","year":2000,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":555,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"School of Medicine, Stanford University; Medical Research Council Canada; Heart and Stroke Foundation of Canada; National Institute of Neurological Disorders and Stroke; Medical Research Council; Korea Science and Engineering Foundation; Johns Hopkins University; Howard Hughes Medical Institute","keywords":"AMPA receptor; Internalization; Silent synapse; Long-term depression; Cell biology; Dynamin; Biology; Ion channel linked receptors; Postsynaptic potential; Neurotransmission; Neuroscience; SGK1; Synaptic plasticity; Glutamate receptor; Receptor; Chemistry; Endocytosis; Biochemistry; Phosphorylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002532142,0.0002315744,0.0002295274,0.0002014831,0.000307643,0.0000907192,0.0009148084,0.000119971,0.0003136267],"category_scores_gemma":[0.001147915,0.0002004891,0.00007345161,0.001134834,0.0008204539,0.0004012134,0.0002629238,0.0006665057,0.00003811158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002337006,"about_ca_system_score_gemma":0.00006982659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000353463,"about_ca_topic_score_gemma":4.405632e-7,"domain_scores_codex":[0.9968513,0.0003320878,0.0003068342,0.001034091,0.0009343288,0.0005413754],"domain_scores_gemma":[0.9990108,0.0002142572,0.0001225258,0.0003521099,0.00005642784,0.0002438845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005680831,0.000128898,0.0001729263,0.00001617381,3.960671e-7,0.0001475551,0.00004971419,0.0000429575,0.9928123,0.004302341,0.00007580901,0.00219407],"study_design_scores_gemma":[0.000333919,0.0003758283,0.001430394,0.00001658241,0.000007087799,0.0001251392,0.000004035929,0.002001232,0.9927425,0.0009948573,0.001797689,0.0001707839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996664,0.00006516735,0.0007571808,0.0002896371,0.000915485,0.0003687207,0.00004081158,0.00008360589,0.0008154286],"genre_scores_gemma":[0.99522,0.0004348285,0.00005871411,0.003818096,0.00002583477,0.00001622317,5.292986e-7,0.00002185635,0.0004039201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003528459,"threshold_uncertainty_score":0.8175708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02534506049770316,"score_gpt":0.303838937405263,"score_spread":0.2784938769075598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}