{"id":"W1507518844","doi":"10.14694/edbook_am.2015.35.e504","title":"Multiple Myeloma: From Front-Line to Relapsed Therapies","year":2015,"lang":"en","type":"review","venue":"American Society of Clinical Oncology Educational Book","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Pomalidomide; Ixazomib; Lenalidomide; Thalidomide; Medicine; Carfilzomib; Multiple myeloma; Bortezomib; Oncology; Internal medicine; Proteasome inhibitor; Refractory (planetary science); Pharmacology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006033478,0.0007699828,0.001387235,0.002372544,0.0003260336,0.001358133,0.001077391,0.001024273,0.004650292],"category_scores_gemma":[0.0008959809,0.000295802,0.0004957257,0.002706283,0.0005760325,0.001791833,0.0009128095,0.002926708,0.003799511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009623964,"about_ca_system_score_gemma":0.000945053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001065858,"about_ca_topic_score_gemma":0.002464288,"domain_scores_codex":[0.9996709,0.00005240935,0.00004012926,0.00004594335,0.0001652029,0.00002547147],"domain_scores_gemma":[0.999686,0.0001122516,0.00005118425,0.00001007749,0.0001002607,0.0000403965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006155316,0.00006082004,0.0001095023,0.0132091,0.00007209167,0.0001785721,0.00006581013,0.000270701,0.0007635271,0.003661705,0.1393185,0.8422281],"study_design_scores_gemma":[0.00001589182,0.00003683682,0.0003075671,0.003857654,0.0000456427,0.0009113806,0.0000294884,0.00003971052,0.00008835363,0.001520495,0.9931376,0.000009445018],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004468276,0.9977497,0.0000539537,0.0005233348,0.0005376191,0.000003193745,0.00001317669,0.0000070556,0.00106727],"genre_scores_gemma":[0.0003261111,0.9973487,0.0001139701,0.0006747831,0.0005738676,0.000004069823,0.00002632919,0.000001909333,0.0009302877],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004650292,"threshold_uncertainty_score":0.01555681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.216861391646842,"score_gpt":0.531727034602765,"score_spread":0.314865642955923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}