{"id":"W1507584445","doi":"10.31083/ph.2010.0621","title":"2-[4-(4-Methoxyphenylcarbonyloxy)benzylidene]-6-dimethylaminomethyl cyclohexanone hydrochloride: A Mannich base which inhibits the growth of some drug-resistant strains of Mycobacterium tuberculosis","year":2010,"lang":"en","type":"article","venue":"˜Die œPharmazie","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Cyclohexanone; Hydrochloride; Mycobacterium tuberculosis; Microbiology; Chemistry; Drug; Tuberculosis; Mannich base; Biology; Biochemistry; Pharmacology; Medicine; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004383763,0.0007104013,0.001794316,0.0007353828,0.0002173286,0.00003520097,0.0008928083,0.0004439692,0.0007193137],"category_scores_gemma":[0.004123353,0.0005172321,0.0006771672,0.001344923,0.0008723926,0.0003794391,0.0005338961,0.001982075,0.00006304481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001205735,"about_ca_system_score_gemma":0.0005654648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001721526,"about_ca_topic_score_gemma":0.0008217959,"domain_scores_codex":[0.9935305,0.0008432055,0.001879814,0.001019593,0.001252276,0.001474609],"domain_scores_gemma":[0.9938204,0.001876063,0.0006968018,0.001667321,0.001105064,0.0008343827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001050344,0.0007292845,0.0153847,0.0009617703,0.000828503,0.00006541466,0.0006057414,0.00001062074,0.9735466,0.001145146,0.004195867,0.001476009],"study_design_scores_gemma":[0.004718265,0.0007953909,0.1647903,0.0002938446,0.0008744356,0.0001119944,0.0003959397,0.0008350839,0.8209694,0.001864306,0.003628535,0.000722515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981031,0.002422948,0.0000397511,0.01094822,0.0007428037,0.001218462,0.0003443045,0.0001185147,0.003133995],"genre_scores_gemma":[0.9937016,0.001645238,0.001511893,0.00120502,0.0009091587,0.0001662432,0.0001390641,0.0001256112,0.000596185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1525772,"threshold_uncertainty_score":0.9997279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01952815014787063,"score_gpt":0.3013272971166646,"score_spread":0.2817991469687939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}