{"id":"W1507584445","doi":"10.31083/ph.2010.0621","title":"2-[4-(4-Methoxyphenylcarbonyloxy)benzylidene]-6-dimethylaminomethyl cyclohexanone hydrochloride: A Mannich base which inhibits the growth of some drug-resistant strains of Mycobacterium tuberculosis","year":2010,"lang":"en","type":"article","venue":"˜Die œPharmazie","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Cyclohexanone; Hydrochloride; Mycobacterium tuberculosis; Microbiology; Chemistry; Drug; Tuberculosis; Mannich base; Biology; Biochemistry; Pharmacology; Medicine; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008387925,0.0001927662,0.0001917243,0.0001178999,0.0001047209,0.000106916,0.0001643004,0.0001931809,0.00222182],"category_scores_gemma":[0.0001322886,0.00008452281,0.00006714863,0.000106298,0.0001370127,0.0001234626,0.0001249155,0.0002490413,0.0005535877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001076312,"about_ca_system_score_gemma":0.0001794087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000350586,"about_ca_topic_score_gemma":0.000811652,"domain_scores_codex":[0.9999317,0.00001684564,0.00000732157,0.00001153784,0.00001587815,0.00001677174],"domain_scores_gemma":[0.9999025,0.00001715025,0.00003674908,0.000009341055,0.000008936569,0.00002531522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002877611,0.00004955631,0.0002925785,0.00007619836,0.000005606869,0.00008351109,0.000009671629,0.00008859392,0.9925686,0.00006104676,0.00006364407,0.006413364],"study_design_scores_gemma":[0.00008815911,0.002315055,0.007961372,0.0000156926,0.00001549681,0.000881864,0.00002124197,0.0002866843,0.9827324,0.0000251286,0.005647731,0.000009050577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877792,0.00550446,0.001516528,0.0001059853,0.00006657412,0.0000487964,0.0001854412,0.00008050915,0.004712556],"genre_scores_gemma":[0.9930913,0.002405826,0.001582996,0.00004145252,0.00003749444,0.00002411168,0.0002138194,0.000009564314,0.002593251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00222182,"threshold_uncertainty_score":0.007432759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01952815014787063,"score_gpt":0.3013272971166646,"score_spread":0.2817991469687939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}