{"id":"W1507664670","doi":"10.1111/cge.12624","title":"Something old, something new: <i>TBK1</i>, a novel gene in known amyotrophic lateral sclerosis pathways","year":2015,"lang":"en","type":"letter","venue":"Clinical Genetics","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Amyotrophic lateral sclerosis; Exome sequencing; Exome; Genetics; Gene; TANK-binding kinase 1; Biology; Medicine; Neuroscience; Bioinformatics; Mutation; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008821288,0.0006715261,0.0009886553,0.0005962276,0.001401851,0.001504951,0.0008075574,0.01433772,0.002775176],"category_scores_gemma":[0.00748528,0.0003635689,0.0008232363,0.0004144156,0.001321859,0.00171735,0.0005490381,0.008853906,0.002054669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001687719,"about_ca_system_score_gemma":0.0006447174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002435526,"about_ca_topic_score_gemma":0.003073442,"domain_scores_codex":[0.9993162,0.0001658349,0.0001343268,0.0001466706,0.000138897,0.00009801809],"domain_scores_gemma":[0.9975897,0.001462155,0.0001828313,0.0001163096,0.000323716,0.0003253883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007677771,0.0001484923,0.01814611,0.0003021099,0.0002029082,0.2754547,0.0006201473,0.0004509525,0.008160842,0.006374196,0.651041,0.03833078],"study_design_scores_gemma":[0.0008662627,0.0005916792,0.02958654,0.001071844,0.0005153345,0.5648361,0.00159535,0.00619455,0.005383626,0.03543931,0.353607,0.0003124011],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.01941503,0.004984234,0.0007201977,0.9502637,0.01748064,0.00003061349,0.0002402245,0.0001436643,0.006721729],"genre_scores_gemma":[0.1714919,0.007221132,0.002107546,0.6757064,0.1277286,0.000056092,0.0002286777,0.000103537,0.01535614],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01433772,"threshold_uncertainty_score":0.0122453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2742506595748455,"score_gpt":0.3861948362769855,"score_spread":0.11194417670214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}