{"id":"W1507690397","doi":"10.1385/1-59259-430-1:121","title":"Green Fluorescent Protein-Tagged β-Arrestin Translocation as a Measure of G Protein-Coupled Receptor Activation","year":2003,"lang":"en","type":"review","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"G protein-coupled receptor; Rhodopsin-like receptors; Arrestin; Cell biology; G protein-coupled receptor kinase; Internalization; Heterotrimeric G protein; Biology; G protein; Chemistry; Receptor; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005473718,0.0009007604,0.001228044,0.002565372,0.0001756137,0.0007021818,0.0008975763,0.001046877,0.001446405],"category_scores_gemma":[0.0003828906,0.0003121227,0.0003059139,0.001983117,0.0007255531,0.0008500249,0.0003709164,0.001558228,0.003633262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001240143,"about_ca_system_score_gemma":0.0004207392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001084794,"about_ca_topic_score_gemma":0.001562805,"domain_scores_codex":[0.9996189,0.00005361238,0.00002580203,0.0001006199,0.0001774896,0.00002351727],"domain_scores_gemma":[0.9998249,0.00006286913,0.00002990631,0.000007667029,0.0000562314,0.00001833673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001671153,0.0001519424,0.0008486076,0.006272793,0.0001030703,0.0006697282,0.00009664406,0.0007011724,0.09975342,0.01082097,0.03095421,0.8494604],"study_design_scores_gemma":[0.00002812461,0.0002148702,0.004943028,0.001018182,0.00008563419,0.004966082,0.0001106595,0.0005534189,0.05282439,0.003574269,0.9316183,0.00006301864],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001417405,0.9863556,0.003545117,0.0004978793,0.0005008682,0.00001545595,0.00006552103,0.00009657023,0.007505554],"genre_scores_gemma":[0.009417663,0.978435,0.002981759,0.0005083834,0.000283072,0.00003932571,0.0001282214,0.00001564091,0.008190862],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002565372,"threshold_uncertainty_score":0.008997977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06054694606736133,"score_gpt":0.2950796783727313,"score_spread":0.23453273230537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}