{"id":"W1507905236","doi":"10.4161/pri.28368","title":"The structure of the infectious prion protein","year":2014,"lang":"en","type":"article","venue":"Prion","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Alberta Prion Research Institute","keywords":"Computational biology; Prion protein; Gene isoform; Molecular model; Protein structure; Biology; Computer science; Biological system; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001866442,0.0003686353,0.0002593866,0.0005224491,0.0003367598,0.0007621112,0.0003919846,0.0008292837,0.0006789995],"category_scores_gemma":[0.0004278257,0.0001816249,0.0002392245,0.000493395,0.0006174975,0.0006853509,0.00024017,0.0006323924,0.0008555399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003802449,"about_ca_system_score_gemma":0.0006014733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007869956,"about_ca_topic_score_gemma":0.0004637417,"domain_scores_codex":[0.9998845,0.00002012633,0.000009244909,0.00003025207,0.00004865417,0.000007249951],"domain_scores_gemma":[0.9999044,0.00002137677,0.00003207048,0.00001306181,0.00002044984,0.000008537805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002860742,0.0001747741,0.006510034,0.003502112,0.0001092469,0.00166573,0.0004949163,0.02282375,0.601544,0.09519351,0.01200805,0.2556879],"study_design_scores_gemma":[0.00004487566,0.001269648,0.0201914,0.0007573913,0.0003656999,0.01026243,0.001051281,0.06341141,0.286302,0.1329722,0.4831696,0.0002020535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5292639,0.2917224,0.1260133,0.004436048,0.001038732,0.0001369179,0.003301921,0.0008513323,0.04323547],"genre_scores_gemma":[0.8125219,0.09788769,0.07478407,0.0006305805,0.0002925388,0.00006035299,0.006155424,0.0000762886,0.007591231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008292837,"threshold_uncertainty_score":0.00275892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002396123359524821,"score_gpt":0.203125178164428,"score_spread":0.2007290548049032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}