{"id":"W1508632532","doi":"10.1186/bcr722","title":"Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer","year":2003,"lang":"en","type":"review","venue":"Breast Cancer Research","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Cancer research; Breast cancer; Cancer; Proteolysis; Regulator; Surgical oncology; Receptor tyrosine kinase; Kinase; Biology; Cyclin; Tyrosine kinase; Signal transduction; Cell cycle; Medicine; Gene; Internal medicine; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001328942,0.0005855515,0.002013971,0.0008920737,0.0001143917,0.00004763314,0.0003178554,0.0006479334,0.0007542401],"category_scores_gemma":[0.0001069809,0.0005365487,0.000303463,0.002384737,0.0002910668,0.0001158964,0.0001460028,0.001714192,0.00002249892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002005157,"about_ca_system_score_gemma":0.005326888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002540624,"about_ca_topic_score_gemma":0.0001950329,"domain_scores_codex":[0.9944696,0.0007761584,0.001083657,0.001150688,0.001475119,0.001044819],"domain_scores_gemma":[0.9974072,0.0003247534,0.0004238588,0.0005575264,0.0008745159,0.0004121471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003457106,0.0003069251,0.000760345,0.03661972,0.0005056455,0.0001016673,0.0001040699,0.00004345671,0.005516272,0.00003895389,0.001806086,0.9538512],"study_design_scores_gemma":[0.008054264,0.0005356655,0.003947167,0.2772609,0.003852521,0.004297012,0.0001368818,0.0004180312,0.003417096,0.00008161821,0.6953315,0.002667271],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001780542,0.9916154,0.00001495509,0.0004128748,0.0001645994,0.003916119,0.001850792,0.00003449126,0.0002102734],"genre_scores_gemma":[0.01283511,0.9839284,0.00003789165,0.00003423737,0.0002619669,0.002060234,0.0001502896,0.0001947518,0.0004971296],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9511839,"threshold_uncertainty_score":0.9997086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09465993212574902,"score_gpt":0.4206266008853011,"score_spread":0.3259666687595521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}