{"id":"W1508890758","doi":"","title":"Cytotoxic and Antioxidant Activity of a Set of Hetero Bicylic Methylthiadiazole Hydrazones: A Structure-Activity Study.","year":2015,"lang":"en","type":"article","venue":"PubMed","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"HeLa; Cytotoxicity; Chemistry; Antioxidant; Moiety; Oxidative stress; Radical; In vitro; Stereochemistry; Cell culture; Cytotoxic T cell; Viability assay; Cancer cell; Docking (animal); Biochemistry; Pharmacology; Cancer; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005473134,0.0002226286,0.0006259698,0.00006574357,0.00003734357,0.00001818053,0.0001958557,0.0001679303,0.00003510885],"category_scores_gemma":[0.0004913374,0.0001612435,0.000103468,0.0001771434,0.0002005552,0.0001539824,0.0001788993,0.0001943568,5.500426e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005311837,"about_ca_system_score_gemma":0.000031412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005304787,"about_ca_topic_score_gemma":0.000103977,"domain_scores_codex":[0.9985462,0.0001601915,0.0002545881,0.0003969665,0.0003086729,0.0003333446],"domain_scores_gemma":[0.9987272,0.000268226,0.0003321711,0.00038982,0.00007052011,0.0002120775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004269441,0.0008042228,0.1061106,0.0001339725,0.0001567829,0.000004347911,0.0002431637,0.000002560854,0.7630288,0.000004836302,0.00000992255,0.1290739],"study_design_scores_gemma":[0.0004957158,0.00006328389,0.4571128,0.000005714047,0.00003354309,0.000004865665,0.0001021066,0.00003116462,0.5418528,0.0001244116,0.00005356838,0.0001199935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986355,0.00008517113,0.00001489538,0.00006165556,0.00004808115,0.0003822557,0.000167277,0.00003960828,0.0005655362],"genre_scores_gemma":[0.9996707,0.00001072251,0.00004201463,0.00000815557,0.00006183649,0.0001642626,0.00000134382,0.00001321224,0.0000277286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3510022,"threshold_uncertainty_score":0.6575318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06575054891928556,"score_gpt":0.2611135795489286,"score_spread":0.1953630306296431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}