{"id":"W1508890758","doi":"","title":"Cytotoxic and Antioxidant Activity of a Set of Hetero Bicylic Methylthiadiazole Hydrazones: A Structure-Activity Study.","year":2015,"lang":"en","type":"article","venue":"PubMed","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"HeLa; Cytotoxicity; Chemistry; Antioxidant; Moiety; Oxidative stress; Radical; In vitro; Stereochemistry; Cell culture; Cytotoxic T cell; Viability assay; Cancer cell; Docking (animal); Biochemistry; Pharmacology; Cancer; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001365436,0.0003058792,0.0002115791,0.0002932037,0.0001678972,0.00008583974,0.0002402422,0.0002029833,0.001228054],"category_scores_gemma":[0.00008175855,0.0001043188,0.0001773132,0.0002478519,0.0001237257,0.0001087254,0.0001242177,0.0002305014,0.000187716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001518738,"about_ca_system_score_gemma":0.0001890996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000769349,"about_ca_topic_score_gemma":0.002738258,"domain_scores_codex":[0.9999532,0.00001114816,0.000004353438,0.000007504111,0.00001208498,0.00001169221],"domain_scores_gemma":[0.9999566,0.000006318382,0.0000129377,0.000005302765,0.000008724765,0.00001006433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004120264,0.0001676138,0.0004073514,0.000372133,0.00002576329,0.0001486148,0.0000382565,0.0005536889,0.9875272,0.0001584665,0.000164701,0.01002417],"study_design_scores_gemma":[0.0001338634,0.008302543,0.009736808,0.00004418814,0.00013155,0.0009278596,0.00006343557,0.001136378,0.9721193,0.0000748548,0.00730681,0.00002244021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827969,0.01215741,0.001630002,0.0001303311,0.0000368624,0.00008245686,0.0004637109,0.00006580997,0.002636384],"genre_scores_gemma":[0.9911344,0.005249384,0.001796474,0.00003887783,0.00001210639,0.00002314746,0.0004137494,0.000003752463,0.001328037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001228054,"threshold_uncertainty_score":0.00410831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06575054891928556,"score_gpt":0.2611135795489286,"score_spread":0.1953630306296431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}