{"id":"W1509023167","doi":"10.1111/j.1600-6143.2011.03763.x","title":"The PROMISE Study: A Phase 2b Multicenter Study of Voclosporin (ISA247) Versus Tacrolimus in De Novo Kidney Transplantation","year":2011,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Tacrolimus; Renal function; Urology; Transplantation; Calcineurin; Clinical endpoint; Incidence (geometry); Kidney transplantation; Internal medicine; Adverse effect; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003665989,0.002295709,0.004101818,0.0005135603,0.000684395,0.001827753,0.001471878,0.001741989,0.004303769],"category_scores_gemma":[0.001967234,0.000819986,0.002380773,0.0004815776,0.00189563,0.002205391,0.0006605923,0.006946966,0.001247878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001034813,"about_ca_system_score_gemma":0.002201317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001032552,"about_ca_topic_score_gemma":0.002244235,"domain_scores_codex":[0.9987811,0.000699483,0.00004585618,0.0001617309,0.00009760109,0.000214125],"domain_scores_gemma":[0.998268,0.0004012306,0.0003677446,0.0001478009,0.00007821354,0.0007370891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9364281,0.02853786,0.002434319,0.0003153153,0.001462828,0.00009799754,0.0001240878,0.0007535077,0.007486046,0.0002553908,0.00159078,0.02051378],"study_design_scores_gemma":[0.8423759,0.1507974,0.003560707,0.00001816247,0.0007381257,0.00009175017,0.00006941006,0.0003931137,0.0008720921,0.000165491,0.0008879143,0.00002990998],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933242,0.001805807,0.0004371189,0.001100894,0.0002589209,0.0009556722,0.0009226559,0.00008432435,0.00111035],"genre_scores_gemma":[0.9862986,0.002407405,0.001944964,0.00186256,0.0007653897,0.002147735,0.001874674,0.00007953721,0.00261895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004303769,"threshold_uncertainty_score":0.01938778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0361847693283588,"score_gpt":0.3423945813448663,"score_spread":0.3062098120165075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}