{"id":"W1509033214","doi":"10.4049/jimmunol.181.4.2772","title":"Human Airway Smooth Muscle Promotes Human Lung Mast Cell Survival, Proliferation, and Constitutive Activation: Cooperative Roles for CADM1, Stem Cell Factor, and IL-6","year":2008,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute for Health and Care Research; Wellcome Trust","keywords":"Degranulation; Mast cell; Stem cell factor; Cell biology; Chemotaxis; Immunology; Cell; Receptor; Biology; Stem cell; Haematopoiesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000194531,0.0002161163,0.0001421278,0.0001497456,0.000127856,0.0002243749,0.0000738247,0.0001096732,0.001846165],"category_scores_gemma":[0.0001268709,0.00007998528,0.0001864432,0.00009649259,0.0001079042,0.0001071073,0.0002347575,0.0002911113,0.0004346547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001464455,"about_ca_system_score_gemma":0.0001438132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006296734,"about_ca_topic_score_gemma":0.001020628,"domain_scores_codex":[0.9998719,0.00003232854,0.000008369611,0.00001568004,0.00003586175,0.00003589312],"domain_scores_gemma":[0.9999239,0.00002153078,0.00001181128,0.00001271192,0.00001039211,0.00001966681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001953689,0.00004714537,0.0005015852,0.00003753656,0.000003717774,0.00007602324,0.00002960804,0.00002829735,0.9965003,0.00005637404,0.00009630348,0.002427858],"study_design_scores_gemma":[0.00005712446,0.0008459877,0.02299141,0.00001057806,0.00002657565,0.00063464,0.00007962594,0.00131285,0.9672608,0.00005553382,0.006721612,0.000003394538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941953,0.002963006,0.001121682,0.0001075377,0.00002018875,0.00002103057,0.0001593826,0.00003915856,0.001372764],"genre_scores_gemma":[0.9965512,0.0009066844,0.0007242092,0.00004129326,0.00002051367,0.00002423684,0.0004010616,0.000005018603,0.001325837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001846165,"threshold_uncertainty_score":0.006176054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02292777986019424,"score_gpt":0.2683576603417673,"score_spread":0.2454298804815731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}