{"id":"W1509126283","doi":"10.1002/0471267295.ch6","title":"pH Dependence of Enzyme‐Catalyzed Reactions","year":2002,"lang":"en","type":"other","venue":"","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Catalysis; Chemistry; Enzyme; Enzyme catalysis; Computational chemistry; Reaction rate; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00004929467,0.0001451011,0.0001731627,0.0000854052,0.0000150214,0.000006050058,0.0001558052,0.0002980748,0.003305551],"category_scores_gemma":[0.00005117772,0.0001303512,0.0001092079,0.00009202831,0.00004931067,0.000001212005,0.00005028371,0.00005112529,0.00007559678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004974901,"about_ca_system_score_gemma":0.00002339602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001238825,"about_ca_topic_score_gemma":0.000139271,"domain_scores_codex":[0.9992903,0.00001993546,0.000193011,0.0002851325,0.0001049556,0.0001066293],"domain_scores_gemma":[0.9992256,0.000003709468,0.0001848277,0.0005023982,0.00004624363,0.00003722769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003605189,0.00006021868,0.00002765414,0.0000430328,0.00007368151,4.008142e-7,0.000003301931,0.000008824482,0.4219342,0.00008772059,0.5773644,0.0003928589],"study_design_scores_gemma":[0.0001165112,0.00002549308,0.000008200876,0.00002763107,0.00003053247,0.00000355536,0.000009384175,0.00001384336,0.3543437,0.00000266527,0.6452945,0.0001239011],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0004726484,0.003527325,0.006368462,0.00001929983,0.0001698127,0.0001921704,0.00007170434,0.00003711874,0.9891415],"genre_scores_gemma":[0.02339087,0.001992501,0.0005500411,0.00003218991,0.0002027585,0.00001421342,0.0009349947,0.0001535002,0.9727289],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.06793007,"threshold_uncertainty_score":0.9976056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01129347212749188,"score_gpt":0.2417477881927493,"score_spread":0.2304543160652575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}