{"id":"W1509126283","doi":"10.1002/0471267295.ch6","title":"pH Dependence of Enzyme‐Catalyzed Reactions","year":2002,"lang":"en","type":"other","venue":"","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Catalysis; Chemistry; Enzyme; Enzyme catalysis; Computational chemistry; Reaction rate; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004119196,0.0009435018,0.0005074784,0.0004489894,0.0002483082,0.001008607,0.001110336,0.0005485754,0.006750704],"category_scores_gemma":[0.0007705251,0.000412122,0.0005469068,0.000389732,0.0004100255,0.001025765,0.0006224343,0.001638429,0.004461197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007976784,"about_ca_system_score_gemma":0.0004098743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003216726,"about_ca_topic_score_gemma":0.0002532179,"domain_scores_codex":[0.9994043,0.00005507477,0.0000287687,0.0001320185,0.0003283937,0.00005153409],"domain_scores_gemma":[0.9997799,0.0001055382,0.00003072493,0.00001962927,0.00005265671,0.00001151052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002109755,0.0001264009,0.0007344664,0.002761651,0.00007900558,0.0004679674,0.0002266098,0.02111262,0.7040057,0.09982113,0.008194682,0.1622588],"study_design_scores_gemma":[0.00001666621,0.0001659212,0.001132992,0.0001195413,0.00004183221,0.0008353616,0.00003697927,0.0313485,0.8505253,0.01869696,0.09702662,0.00005332037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"other","genre_scores_codex":[0.0813197,0.08519053,0.6677803,0.001968022,0.001549873,0.0004819504,0.002327987,0.002750094,0.1566316],"genre_scores_gemma":[0.6400565,0.1507935,0.1198036,0.001443125,0.0005825368,0.0006247914,0.003569926,0.0006193153,0.08250665],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.006750704,"threshold_uncertainty_score":0.02258337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01129347212749188,"score_gpt":0.2417477881927493,"score_spread":0.2304543160652575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}