{"id":"W1509157729","doi":"10.1021/acs.orglett.5b00128","title":"One-Pot Synthesis of 3,4,5-Trisubstituted 1,2,4-Triazoles via the Addition of Hydrazides to Activated Secondary Amides","year":2015,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre in Green Chemistry and Catalysis","funders":"Fonds de recherche du Québec – Nature et technologies; Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Chemistry; Moiety; Intramolecular force; Combinatorial chemistry; Catalysis; Surface modification; Functional group; Reaction conditions; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001848558,0.0005547445,0.0004223209,0.0002267336,0.0002082912,0.0001613172,0.0006393063,0.000293478,0.002322413],"category_scores_gemma":[0.00009448685,0.0001904598,0.0003366869,0.0002400402,0.0001767746,0.000257731,0.0002642091,0.0005109257,0.0008091558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002910014,"about_ca_system_score_gemma":0.0003871693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005120534,"about_ca_topic_score_gemma":0.001921664,"domain_scores_codex":[0.9998908,0.00001032551,0.00001362144,0.00002214831,0.00002103084,0.00004218431],"domain_scores_gemma":[0.9999541,0.000005040583,0.00001255209,0.000006256534,0.000007492692,0.00001461365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006929188,0.00007092238,0.00008751122,0.0002539583,0.00001938778,0.0004267679,0.00008876353,0.0004349749,0.9903961,0.0007345868,0.0003078143,0.00710995],"study_design_scores_gemma":[0.00006499426,0.0007942251,0.001038044,0.00001138388,0.00003820881,0.000664413,0.00003072914,0.001145868,0.9884477,0.0001358571,0.00760081,0.0000276577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9385509,0.004928168,0.03924563,0.0002793841,0.000220052,0.0004701363,0.001614814,0.0009320559,0.01375867],"genre_scores_gemma":[0.977,0.002710526,0.01414349,0.00006965476,0.00002707194,0.0001314331,0.0006097415,0.00003878151,0.005269292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002322413,"threshold_uncertainty_score":0.007769227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02401652258417861,"score_gpt":0.2479844420310807,"score_spread":0.2239679194469021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}