{"id":"W1510051491","doi":"10.1001/jama.2015.3860","title":"Fixed-Dose Combination Therapy With Daclatasvir, Asunaprevir, and Beclabuvir for Noncirrhotic Patients With HCV Genotype 1 Infection","year":2015,"lang":"en","type":"article","venue":"JAMA","topic":"Hepatitis C virus research","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Infectious Diseases Centre; University of Calgary","funders":"","keywords":"Daclatasvir; Medicine; Internal medicine; Sofosbuvir; Ribavirin; Gastroenterology; Hepatitis C; Hepatitis C virus; NS5A; Hepacivirus; Virology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007905075,0.0003751838,0.001084233,0.0003516395,0.0003427999,0.0003286503,0.0003761562,0.0003961811,0.001249454],"category_scores_gemma":[0.001115061,0.000256703,0.0005718559,0.0004295431,0.0003852265,0.0004001815,0.0001658899,0.0006193786,0.0001765104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005287797,"about_ca_system_score_gemma":0.0007669634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001032442,"about_ca_topic_score_gemma":0.003730554,"domain_scores_codex":[0.9994577,0.000252033,0.00006078514,0.00007656137,0.00009658367,0.00005640051],"domain_scores_gemma":[0.9994851,0.00008628557,0.0002091398,0.00003057177,0.00003714604,0.0001516721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3634066,0.03098194,0.2640121,0.001646511,0.002467857,0.0006000118,0.0005102973,0.002117048,0.02419547,0.0001606649,0.002199839,0.3077018],"study_design_scores_gemma":[0.1205026,0.4517699,0.4142933,0.0001971194,0.001160319,0.001360532,0.0002604852,0.002519543,0.003633034,0.0001938384,0.004043023,0.00006626598],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962405,0.002587688,0.0001538719,0.00007439291,0.00002901772,0.0003014413,0.00009161242,0.0000143886,0.0005071347],"genre_scores_gemma":[0.9980014,0.0007214042,0.0005710893,0.0001219659,0.00005347512,0.000197185,0.0001247795,0.000001695533,0.0002070093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001249454,"threshold_uncertainty_score":0.00418067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0432192685126097,"score_gpt":0.3084576007420517,"score_spread":0.265238332229442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}