{"id":"W1510897779","doi":"10.1002/9780470522226.ch19","title":"Topical and Systemic Drug Delivery Systems for Targeted Therapy","year":2009,"lang":"en","type":"other","venue":"","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Transdermal; Drug; Drug delivery; Medicine; Pharmacology; Skin barrier; Dermatology; Nanotechnology; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002270919,0.0006225503,0.0005564083,0.0007781868,0.0003462713,0.0009355146,0.0004222341,0.0005636147,0.03380861],"category_scores_gemma":[0.0001185023,0.0002021749,0.0003749171,0.000631868,0.0002227587,0.001069337,0.0006598966,0.001039385,0.02029937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004061009,"about_ca_system_score_gemma":0.0004011195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004722949,"about_ca_topic_score_gemma":0.001005605,"domain_scores_codex":[0.9998143,0.00001333997,0.000007746101,0.00003492576,0.0001107352,0.00001891232],"domain_scores_gemma":[0.9999607,0.000007391964,0.000006211789,0.000004578832,0.00001533612,0.000005835552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007874789,0.0001279672,0.00008564869,0.001835178,0.00001889171,0.0002516824,0.00007987974,0.0005756047,0.3135763,0.01436642,0.0624616,0.6065421],"study_design_scores_gemma":[0.00001406389,0.0001408405,0.0003540466,0.0001798269,0.00002092542,0.0006289019,0.00002573763,0.0005436911,0.08431257,0.001711458,0.912047,0.00002097378],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.01270257,0.3739448,0.1145361,0.002620306,0.004998385,0.0007620777,0.002620948,0.002718292,0.4850966],"genre_scores_gemma":[0.04276127,0.3026217,0.05979344,0.001996998,0.001412922,0.0005017149,0.001861581,0.000421706,0.5886287],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03380861,"threshold_uncertainty_score":0.1131011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06897389761183269,"score_gpt":0.3946842809145068,"score_spread":0.3257103833026741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}