{"id":"W1510897779","doi":"10.1002/9780470522226.ch19","title":"Topical and Systemic Drug Delivery Systems for Targeted Therapy","year":2009,"lang":"en","type":"other","venue":"","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Transdermal; Drug; Drug delivery; Medicine; Pharmacology; Skin barrier; Dermatology; Nanotechnology; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002879336,0.0004661884,0.0006153526,0.0001833722,0.0001231731,0.00002684529,0.0002939561,0.0008375056,0.002199013],"category_scores_gemma":[0.00001072367,0.0004063734,0.0001232432,0.00007153808,0.0001515218,0.00005064004,0.00003346413,0.0005722849,0.00009047811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006935388,"about_ca_system_score_gemma":0.00006273753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009806383,"about_ca_topic_score_gemma":0.00002646889,"domain_scores_codex":[0.9980354,0.0002876268,0.0004093122,0.0005505151,0.0001587466,0.0005584065],"domain_scores_gemma":[0.9989935,0.0002853814,0.0001914844,0.0002564022,0.00005840198,0.0002149013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003835274,0.0001960744,0.0002277384,0.0006214482,0.0006736049,0.00003459577,0.0001449462,0.0001028879,0.001137315,0.001442328,0.9598532,0.03518238],"study_design_scores_gemma":[0.002587641,0.0001144661,0.00001979997,0.0001368794,0.0001442628,0.00003433122,0.00008701574,0.001123576,0.0004688825,0.00007736203,0.9947253,0.0004804205],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.007020654,0.3909994,0.009506997,0.000792129,0.01252453,0.01082152,0.001344449,0.001924646,0.5650657],"genre_scores_gemma":[0.02246337,0.04978437,0.0007054145,0.002954325,0.001562433,0.0003736662,0.0001912249,0.0004371826,0.921528],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.3564623,"threshold_uncertainty_score":0.9998388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06897389761183269,"score_gpt":0.3946842809145068,"score_spread":0.3257103833026741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}