{"id":"W15114388","doi":"","title":"Epigenetic transfer of metastatic activity by uptake of highly metastatic B16 melanoma cell-released exosomes.","year":2006,"lang":"en","type":"article","venue":"PubMed","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency","funders":"","keywords":"Melanoma; Flow cytometry; Metastasis; Microvesicles; Cancer research; Cell; Circulating tumor cell; Antigen; Cell culture; Primary tumor; Antibody; Medicine; Pathology; Chemistry; Biology; Cancer; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001808397,0.0003237666,0.0002775135,0.0001319373,0.0000993565,0.0003120459,0.0001650529,0.0003330488,0.001235897],"category_scores_gemma":[0.0001483898,0.0001103937,0.000306185,0.00008050877,0.0001614608,0.0003560099,0.0002714179,0.0005853731,0.0003149531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001910118,"about_ca_system_score_gemma":0.0001174296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001905597,"about_ca_topic_score_gemma":0.0002977097,"domain_scores_codex":[0.9998653,0.00001954036,0.000008741224,0.00003023612,0.00004049734,0.0000356472],"domain_scores_gemma":[0.9999233,0.00001648899,0.00002584195,0.00001203409,0.000007970808,0.0000142632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006787905,0.00004968614,0.0001593915,0.00006362978,0.000005872674,0.00004370238,0.00001265383,0.00005628245,0.9975311,0.0000982296,0.00005649401,0.001855045],"study_design_scores_gemma":[0.00002839614,0.0009239526,0.003373914,0.00001383756,0.00002413634,0.0002421273,0.00003216471,0.0008135922,0.9910775,0.00005316777,0.003412456,0.000004823071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899636,0.002482901,0.00481478,0.0001659661,0.00009480176,0.00008066087,0.0003685416,0.0001016842,0.001927014],"genre_scores_gemma":[0.9941537,0.001206089,0.001681682,0.00005173907,0.00001147911,0.00005513039,0.0003020126,0.00001909497,0.002519067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001235897,"threshold_uncertainty_score":0.004134476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00956050948901207,"score_gpt":0.2036412658015282,"score_spread":0.1940807563125161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}