{"id":"W1511490497","doi":"10.1111/j.1476-5381.2011.01467.x","title":"The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine‐induced dopamine elevations in the nucleus accumbens shell in rats","year":2011,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; U.S. Department of Health and Human Services; National Institutes of Health; Centre for Addiction and Mental Health; University of Toronto; Johns Hopkins University","keywords":"Nucleus accumbens; Nicotine; Dopamine; Pharmacology; Chemistry; Endocannabinoid system; Neuroscience; Anandamide; Endocrinology; Internal medicine; Medicine; Psychology; Cannabinoid receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014512,0.0007518181,0.0005433933,0.0005505985,0.0003517929,0.0002820946,0.0004547778,0.0006112145,0.002003753],"category_scores_gemma":[0.0001569036,0.0003513735,0.0004858285,0.0002106266,0.0004717678,0.0004295502,0.0002318174,0.001171445,0.0004602708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007276821,"about_ca_system_score_gemma":0.0007173629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003329259,"about_ca_topic_score_gemma":0.006222404,"domain_scores_codex":[0.9998333,0.00001600084,0.00001241615,0.00003063339,0.00006221874,0.0000453503],"domain_scores_gemma":[0.9998083,0.00001006853,0.00005779105,0.00001645945,0.00002621952,0.00008120943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001039062,0.0003443196,0.0003764731,0.00005627143,0.00002892889,0.00007764288,0.00002625839,0.0000707053,0.995423,0.000110682,0.00008975537,0.002356975],"study_design_scores_gemma":[0.0001638326,0.004561281,0.01102536,0.00002174159,0.00009012257,0.0003046337,0.00009052527,0.001737652,0.9802925,0.0001699879,0.00152281,0.0000196608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969636,0.0008028065,0.0006767478,0.000174362,0.0000447078,0.00002564548,0.0002542671,0.0001508943,0.000906994],"genre_scores_gemma":[0.9922727,0.001261574,0.001590785,0.00009664473,0.00002626098,0.00007853542,0.0004257502,0.00003613472,0.004211578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003329259,"threshold_uncertainty_score":0.006703258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02169126794254682,"score_gpt":0.3041248206564783,"score_spread":0.2824335527139315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}