{"id":"W1511554937","doi":"10.1111/j.1476-5381.2011.01496.x","title":"Antibodies against the cardiac sodium/bicarbonate co-transporter (NBCe1) as pharmacological tools","year":2011,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Fondation pour la Recherche Médicale; Sanofi; Aarhus Universitet; Agencia Nacional de Promoción Científica y Tecnológica; Heart and Stroke Foundation of Canada; Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Chemistry; Extracellular; Internal medicine; Endocrinology; Acidosis; Depolarization; Potassium; Stimulation; Intracellular pH; Potassium channel; Ion transporter; Biochemistry; Biology; Medicine; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004942849,0.0001703674,0.0002907687,0.00004766188,0.0001550211,0.00002795613,0.0003555974,0.0001861388,0.0004431961],"category_scores_gemma":[0.00001382907,0.0001448073,0.000330394,0.00006894289,0.0002816783,0.00002066819,0.00002555265,0.000330945,0.00001266683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001407771,"about_ca_system_score_gemma":0.0001082166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001239012,"about_ca_topic_score_gemma":0.000004502928,"domain_scores_codex":[0.9985873,0.0001799372,0.0004930331,0.0002108227,0.0002009017,0.0003279987],"domain_scores_gemma":[0.9992827,0.00002172131,0.0002743637,0.00006667151,0.0002392048,0.0001152919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000663867,0.0001980052,0.00316826,0.00001304722,0.000544169,0.0006715533,0.0001864627,0.00002844223,0.9633878,0.00002067436,0.01852612,0.01259164],"study_design_scores_gemma":[0.00208524,0.0004909587,0.04883978,0.00002429174,0.0003872366,0.000954725,0.0001602897,0.00001187657,0.8785252,0.0001055449,0.06812615,0.0002887097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919112,0.003118006,0.0001453045,0.0002527797,0.001464173,0.0002045962,0.00004106062,0.00001101383,0.002851852],"genre_scores_gemma":[0.9907028,0.006273495,0.0001009932,0.00127939,0.001232596,0.00001180896,0.00006442897,0.00002261607,0.0003118423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08486257,"threshold_uncertainty_score":0.5905072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02386763015845899,"score_gpt":0.2785885460134115,"score_spread":0.2547209158549525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}