{"id":"W1511554937","doi":"10.1111/j.1476-5381.2011.01496.x","title":"Antibodies against the cardiac sodium/bicarbonate co-transporter (NBCe1) as pharmacological tools","year":2011,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Fondation pour la Recherche Médicale; Sanofi; Aarhus Universitet; Agencia Nacional de Promoción Científica y Tecnológica; Heart and Stroke Foundation of Canada; Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Chemistry; Extracellular; Internal medicine; Endocrinology; Acidosis; Depolarization; Potassium; Stimulation; Intracellular pH; Potassium channel; Ion transporter; Biochemistry; Biology; Medicine; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006448685,0.001048877,0.0004767641,0.0006745321,0.0004150417,0.0003666993,0.0009164307,0.001162958,0.003708415],"category_scores_gemma":[0.0004059016,0.0004804738,0.0006680978,0.0003144898,0.0004162643,0.0005565738,0.0004661901,0.00151625,0.001692321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006213658,"about_ca_system_score_gemma":0.0003265827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003866957,"about_ca_topic_score_gemma":0.0007366398,"domain_scores_codex":[0.9993875,0.0001072219,0.00007003139,0.00016056,0.0001285208,0.0001460387],"domain_scores_gemma":[0.9995291,0.0001059257,0.0001200847,0.00004474682,0.0001103335,0.00008981294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008263775,0.00003065787,0.00009379697,0.00008855055,0.000007355454,0.00002658313,0.000007042009,0.00001887489,0.9983029,0.00008672462,0.0001254124,0.001129424],"study_design_scores_gemma":[0.00008303252,0.0003818589,0.002754231,0.00003528051,0.00006724666,0.0008586333,0.00002263169,0.0006319577,0.9841399,0.0001006407,0.01091255,0.00001195202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8640248,0.02686745,0.09083579,0.002813344,0.001093499,0.0006843717,0.002564278,0.001072125,0.01004431],"genre_scores_gemma":[0.821036,0.02228701,0.122227,0.001918299,0.0004087986,0.001637643,0.008442346,0.0003492634,0.02169355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003708415,"threshold_uncertainty_score":0.01240593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02386763015845899,"score_gpt":0.2785885460134115,"score_spread":0.2547209158549525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}